[Genetics] Fwd: EBC: Graduate course on sequence data analysis
Pekka Pamilo
pekka.pamilo@oulu.fi
Tue, 01 Jun 2004 14:13:16 +0300
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Information on a course in Uppsala in two parts (September and March). This=
=20
probably overlaps (partly) with the course in Oulu last December. Pekka
>Graduate course: Analysis of sequence data (in two parts).
>
>Part I: Basic coalescent theory (Paul Joyce, University of Idaho, USA, and=
=20
>Martin Lascoux, EBC). September 6-10 2004
>Part II: Applications (Gil McVean, University of Oxford, UK and Martin=20
>Lascoux, EBC). Spring 2005. Tentative date: 14/3-17/3 (this may change=20
>later on).
>
>Credits: 4 points (2 for attendance + 2 for homework). If only one part is=
=20
>attended 2 points.
>
>Aim of the course: Introduce the necessary theoretical background to carry=
=20
>out the analysis of DNA sequence data (part 1) and go through various=20
>applications (estimation of population recombination rate, detection of=20
>recombination hotspots, detection of selection, estimation of past=20
>demographics, part 2).
>
>Target group: Students studying evolutionary biology in general,=20
>especially those using genetics. The course will also be relevant for=20
>students working in gene mapping.
>
>Recommended background: Basic knowledge of genetics, basic knowledge=20
>of basic probability and statistics
>
>Content: Lectures, Exercises, Computer based assignments. Simulation and=20
>analysis of empirical datasets.
>
>Preliminary outline:
>
>Part I
>Intro, basic probability, stochastic processes, statistics.
>The standard coalescent
>Estimation of parameters. Computationally simple methods.
>Estimation of parameters. Computationally intensive methods
>Extension of the coalescent: Recombination and selection graphs
>
>Part II
>The coalescent: a reminder
>Modelling and detecting selection
>Recombination: Estimating the population recombination rate
>LD and haplotypes. Haplotype blocks
>Association mapping
>
>Registration: Send an email to Martin Lascoux at Martin.Lascoux@ebc.uu.se=
=20
>before August 1. You can register for only one part, but I strongly=20
>recommend attending both as they complement each other. For those coming=20
>from other universities please note that we do not arrange housing.
>
>Both Paul and Gil are outstanding teachers. Paul already gave a course at=
=20
>the EBC a few years ago along the same lines. Here is one of the many=20
>positive comments on the course: "cheers for a great course which gave me=
=20
>lots of ideas for analysing data and thinking about polymorphism. As I=20
>mentioned at the time, I really wish I had gone to such a course when I=20
>was a postgrad" (one of the postdoctoral fellow that attended the course).
>
>Welcome!
>
>Martin
>
>Martin Lascoux
>Program in Conservation Biology & Genetics
>Evolutionary Biology Centre
>Uppsala University
>Norbyv=E4gen 18D 752 36 UPPSALA
>SWEDEN
>
>Tel: 46 18 471 64 16
>Fax: 46 18 471 64 24
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<body>
Information on a course in Uppsala in two parts (September and March).
This probably overlaps (partly) with the course in Oulu last December.
Pekka<br><br>
<br>
<blockquote type=3Dcite class=3Dcite cite><font color=3D"#000080"><b>Graduat=
e
course: Analysis of sequence data (in two parts).<br><br>
</font>Part I</b>: Basic coalescent theory (Paul Joyce, University of
Idaho, USA, and Martin Lascoux, EBC). <i>September 6-10 2004<br>
</i><b>Part II</b>: Applications (Gil McVean, University of Oxford, UK
and Martin Lascoux, EBC). <i>Spring 2005. Tentative date: 14/3-17/3</i>
(this may change later on).<br><br>
<b>Credits</b>: 4 points (2 for attendance + 2 for homework). If only one
part is attended 2 points.<br><br>
<b>Aim of the course</b>: Introduce the necessary theoretical background
to carry out the analysis of DNA sequence data (part 1) and go through
various applications (estimation of population recombination rate,
detection of recombination hotspots, detection of selection, estimation
of past demographics, part 2).<br><br>
<b>Target group</b>: Students studying evolutionary biology in general,
especially those using genetics. The course will also be relevant for
students working in gene mapping.<br><br>
<b>Recommended background</b>: Basic knowledge of genetics, basic
knowledge of basic probability and statistics<br><br>
<b>Content</b>: Lectures, Exercises, Computer based assignments.
Simulation and analysis of empirical datasets.<br><br>
Preliminary outline:<br><br>
<b>Part I<br>
</b>Intro, basic probability, stochastic processes, statistics.<br>
The standard coalescent<br>
Estimation of parameters. Computationally simple methods.<br>
Estimation of parameters. Computationally intensive methods<br>
Extension of the coalescent: Recombination and selection graphs<br>
<br>
<b>Part II<br>
</b>The coalescent: a reminder<br>
Modelling and detecting selection<br>
Recombination: Estimating the population recombination rate<br>
LD and haplotypes. Haplotype blocks<br>
Association mapping<br><br>
<b>Registration</b>: Send an email to Martin Lascoux at
<b><i>Martin.Lascoux@ebc.uu.se</i> </b>before <b>August 1</b>. You can
register for only one part, but I strongly recommend attending both as
they complement each other. For those coming from other universities
please note that we do not arrange housing.<br><br>
Both Paul and Gil are outstanding teachers. Paul already gave a course at
the EBC a few years ago along the same lines. Here is one of the many
positive comments on the course: "cheers for a great course which
gave me lots of ideas for analysing data and thinking about
polymorphism. As I mentioned at the time, I really wish I had gone
to such a course when I was a postgrad" (one of the postdoctoral
fellow that attended the course).<br><br>
Welcome!<br><br>
Martin<br><br>
Martin Lascoux<br>
Program in Conservation Biology & Genetics<br>
Evolutionary Biology Centre<br>
Uppsala University<br>
Norbyv=E4gen 18D 752 36 UPPSALA<br>
SWEDEN<br><br>
Tel: 46 18 471 64 16<br>
Fax: 46 18 471 64 24 </blockquote></body>
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--=====================_18501283==_--