Special Seminar on Bioinformatics

Time: Tuesday, 14, March 2017 at 12:15

Location: Auditorium TA101

Presenter: Babak Khalaj

Professor of Electrical Engineering

Sharif University of Technology

https://scholar.google.com/citations?user=8HsoXAUAAAAJ

Title: Information Theoretic Views on Genome Processing

Abstract:

In this talk, we will discuss how views from Information Theory can be adopted in Genomics to identify new bounds on the number of reads required to achieve given performance levels in downstream analysis. Along this path, a new read "termination" policy will be introduced to reduce the required the number of reads for a given coverage. Interestingly, we will show that the well-known Waterman-Lander bound can be broken under the new framework leading to much less number of reads required to achieve whole genome coverage. As another example, the case of DNA Pool sequencing will be presented where we investigate theoretic bounds on DNA fragment lengths to lower the tagging ratio or, in an extreme case, alleviate the need for tagging. Finally, a new alignment scheme, known as Meta-Aligner, will also be proposed that shows promising results in long read alignment.

All Welcome!

Kind regards,

Nader

Dr Nader Aryamanesh

Senior Postdoctoral Research Fellow

Department of Ecology and Genetics

FIN-90014 University of Oulu

Finland

Phone: +358 294 481 442

Mobile: +358 505298362

Email: Nader.Aryamanesh@oulu.fi