Dear colleagues,

A reminder about today's Biology Thursday seminar:

10th Oct 12:15 in zoom (link below), with Prof. Frédéric Guillaume, Organismal and Evolutionary Biology Research Programme, Univ. Helsinki, on:

Gene expression evolution during adaptation to heat and drought stress in Tribolium castaneum

Understanding the genetic basis of trait variation and adaptation is central to evolutionary biology. In my talk, I will present the results of an experimental evolution experiment with the red flour beetle, Tribolium castaneum, in which we adapted replicated lines of the beetle to heat and drought stress. We studied the evolutionary changes in individual fitness, gene expression and allele frequencies with control crosses in transplant experiments after 20 generations of adaptation. Thanks to estimates of genetic variance and covariance of fitness and gene expression, we could show that gene expression evolved as predicted from estimates of genetic selection. Our approach allows us to better understand the genetics of adaptation by linking evolutionary changes in allele frequencies and gene expression with selection intensities and gene properties such as centrality in co-expression networks and pleiotropy. Overall, we found that genes with central positions in co-expression networks were under stronger selection, evolved more and where more likely to carry expression quantitative trait loci (eQTL).

More info at:

https://researchportal.helsinki.fi/en/persons/fr%C3%A9d%C3%A9ric-guillaume

https://scholar.google.fi/citations?hl=fi&user=D_V9RcwAAAAJ&view_op=...

https://www.helsinki.fi/en/researchgroups/eco-evolutionary-dynamics

See you at noon,

Heikki

Heikki Helanterä is inviting you to a scheduled Zoom meeting.

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Meeting ID: 629 1776 3539

Passcode: 166151

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Meeting ID: 629 1776 3539

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=============================================== Heikki Helanterä Professor Ekologian ja genetiikan tutkimusyksikkö / Ecology and Genetics Research Unit Oulun Yliopisto / University of Oulu / Finland heikki.helantera@oulu.fimailto:heikki.helantera@oulu.fi +358 50 4700 545