Crc January 2019

crc@lists.oulu.fi

10 participants
31 discussions

FW: Precision mammalian model development / rat models - INFRAFRONTIER2020 Project - Trans-national Access call - January 2019
by Reetta Hinttala 22 Jan '19

22 Jan '19

[https://www.infrafrontier.eu]<https://www.infrafrontier.eu> INFRAFRONTIER Research Infrastructure INFRAFRONTIER2020 Project - Trans-national Access call - January 2019 Precision rat model development Call information and application form Context and aim of the call INFRAFRONTIER is the European Research Infrastructure for phenotyping and archiving of model mammalian genomes. The INFRAFRONTIER Research Infrastructure provides access to first-class tools and data for biomedical research, and thereby contributes to improving the understanding of gene function in human health and disease using rodent models. The core services of INFRAFRONTIER comprise the systemic phenotyping of mouse mutants in the participating mouse clinics, and the archiving and distribution of mouse mutant lines by the European Mouse Mutant Archive (EMMA) (www.infrafrontier.eu<https://www.infrafrontier.eu/>). Main objective of this INFRAFRONTIER open call is to facilitate access for the wider biomedical research community to the unique infrastructure and scientific expertise of the participating INFRAFRONTIER partners, to deliver novel rat mutant models that will advance knowledge of human disease and will be of widespread use in biomedical science. Many cognitive and physiological characteristics that make the rat an ideal human disease model and choice for laboratory studies in neurobiology, cardiobiology, and immunology. Recent advances in genome-editing technology will be used to develop new rat models of human disease. INFRAFRONTIER will provide open access to all newly developed disease models through the European Mouse Mutant Archive (EMMA). Access to this free-of-charge-service will be granted on the basis of the applicant’s research plans and the potential impact of the proposed novel rat model on the wider biomedical research community. This Trans-national Access call of the INFRAFRONTIER2020 project supports a total of 3 precision rat model development projects. A complementary call provides support for 12 customised mouse model development projects. More information and call application form: https://www.infrafrontier.eu/resources-and-services/infrafrontier-open-call… Proposal submission to proposals(a)infrafrontier.eu<mailto:proposals@infrafrontier.eu> by 15 February 2019. Proposal evaluation from 15 February 2019 to 15 March 2019. The INFRAFRONTIER2020 project has received funding from the EU Research and Innovation programme Horizon 2020 (H2020-EU.1.4.1.1. Developing new world class research infrastructures) www.infrafrontier.eu<https://www.infrafrontier.eu/> and https://twitter.com/InfrafrontierEU Trans-national Access (TA) activity of the INFRAFRONTIER2020 project Free of charge precision mammalian model development service / Access modalities · The EC Horizon 2020 funded INFRAFRONTIER2020 project (2017 – 2020) supports eligible customers with a free-of-charge rat model development service implemented as a Trans-national Access activity supporting a total of 3 projects in this call. · The access unit offered covers the production of a single F1 genome-edited rat line (at least one individual of a F1 genome edited rat line will be provided). · The model development service using genome editing involves project design, preparation of sgRNAs and Cas9 mRNA/protein, and injection into zygotes to generate F0 founder mutant animals (Sprague Dawley genetic background).Selected F0 animals (very often mosaic) will be bred to germ line to produce F1 genome edited animals. Possible allele types that can be generated are indels, exon deletions (< 10kb) and point mutation insertions. · Newly developed rat models will be made available to selected applicants within an average of 12 months following provision of all required information to start the rat production. · The generated rat models will be made available to the scientific community. An optional grace period of up to 1 year for rat models may apply, with immediate release of rat resources after expiry of the grace period. Rat mutant lines will be deposited into the INFRAFRONTIER/EMMA repository for subsequent use by the scientific community. Newly developed rat models will be owned by the production centres and will be distributed by the INFRAFRONTIER/EMMA repository using their institutional MTAs. · Costs: The access to the INFRAFRONTIER2020 model development service is free of charge. However, the shipment cost of the newly developed rat models must be borne by the applicants. · Eligibility: The INFRAFRONTIER2020 Trans-national Access call is open and proposals can be submitted from applicants around the world. Two projects must be allocated to applicants from EU Member States and Associated Countries, and one project can be allocated to applicants from third countries. · Application: Service requests for the INFRAFRONTIER2020 model development service can be made via an application form<https://www.infrafrontier.eu/resources-and-services/infrafrontier-open-call…>. Applications for the Trans-national Access activity must include a short description of the research plans for utilising the newly developed rat model that is being generated by the INFRAFRONTIER2020 TA service. · Selection procedure: Proposals from eligible customers for free of charge access to the INFRAFRONTIER2020 rat model development service will be subject to a review procedure. The review will be based on short descriptions of the projects involving the rat mutants that will be produced by the TA service. A mixed panel of members of INFRAFRONTIER and of an external Evaluation Committee will assess service requests supported by the TA activity. In addition to scientific merit of applicants, soundness of the proposal and research plans, and the beneficial impact of the proposed novel mouse line on the wider biomedical research community will be assessed. Applicants will be informed on the outcome of the evaluation within 6 weeks after the end of the call for which the TA application was submitted. All applications will be handled with strict confidentiality. · Acknowledgements: Please do acknowledge any support under this scheme in all resulting publications with "Part of this work has been funded by the European Union Research and Innovation programme Horizon 2020 (Grant Agreement Number 730879). The participating infrastructure which provided the service should be specifically mentioned in any publication resulting from the service. INFRAFRONTIER - the European research infrastructure for the generation, phenotyping, archiving and distribution of mammalian models https://www.infrafrontier.eu If you do not wish to receive any further communications or wish to unsubscribe, please follow this link INFRAFRONTIER newsletter form<https://www.infrafrontier.eu/infrafrontier-newsletter/> © INFRAFRONTIER 2019 - all rights reserved

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FW: [EMMA/INFRAFRONTIER directors] Precision mammalian model development / mouse models - INFRAFRONTIER2020 Project -Trans-national Access call - January 2019
by Reetta Hinttala 22 Jan '19

22 Jan '19

[https://www.infrafrontier.eu]<https://www.infrafrontier.eu> INFRAFRONTIER Research Infrastructure INFRAFRONTIER2020 Project - Trans-national Access call - January 2019 Precision mouse model development Call information and application form Context and aim of the call INFRAFRONTIER is the European Research Infrastructure for phenotyping, archiving and distribution of model mammalian genomes. The INFRAFRONTIER Research Infrastructure provides access to first-class tools and data for biomedical research, and thereby contributes to improving the understanding of gene function in human health and disease using the mouse model. The core services of INFRAFRONTIER comprise the systemic phenotyping of mouse mutants in the participating mouse clinics, and the archiving and distribution of mouse mutant lines by the European Mouse Mutant Archive (EMMA) (www.infrafrontier.eu<https://www.infrafrontier.eu>). Main objective of this INFRAFRONTIER open call is to facilitate access for the wider biomedical research community to the unique infrastructure and scientific expertise of the participating INFRAFRONTIER partners, to deliver novel mouse lines that will advance knowledge of human disease and will be of widespread use in biomedical science. Recent advances in genome editing technology will be used to develop new mouse models of human disease. INFRAFRONTIER will provide open access to all newly developed disease models through the European Mouse Mutant Archive (EMMA). Access to this free-of-charge-service will be granted on the basis of the applicant’s research plans and the potential impact of the proposed novel mouse line on the wider biomedical research community. This Trans-national Access call of the INFRAFRONTIER2020 project supports a total of 12 precision mouse model development projects. A complementary call provides support for 3 customised rat model development projects. More information and call application form: https://www.infrafrontier.eu/resources-and-services/infrafrontier-open-call… Proposal submission to proposals(a)infrafrontier.eu<mailto:proposals@infrafrontier.eu> by 15 February 2019. Proposal evaluation from 15 February 2019 to 15 March 2019. The INFRAFRONTIER2020 project has received funding from the EU Research and Innovation programme Horizon 2020 (H2020-EU.1.4.1.1. Developing new world class research infrastructures) www.infrafrontier.eu<https://www.infrafrontier.eu> and https://twitter.com/InfrafrontierEU Trans-national Access (TA) activity of the INFRAFRONTIER2020 project Free of charge precision mammalian model development service / Access modalities · The EC Horizon 2020 funded INFRAFRONTIER2020 project (2017 – 2020) supports eligible customers with a free-of-charge mouse model development service implemented as a Trans-national Access activity supporting a total of 12 projects in this call. · The access unit offered covers the production of a single F1 genome-edited mouse line (at least one individual of a F1 genome edited mouse line will be provided). · The model development service involves project design including prediction of off-target sites, preparation of sgRNA’s and Cas9 mRNA/protein, and injection into zygotes to generate F0 founder mutant animals (C57BL/6N or C57BL/6J genetic background preferred). Selected F0 animals will be bred to germ line to produce F1 genome edited animals. Possible allele types that can be generated are indels, exon deletions (< 10kb) and point mutation insertions. Newly developed mouse models will be made available to selected applicants within an average of 12 months following provision of all required information to start the mouse production. · The generated mouse models will be made available to the scientific community. An optional grace period of up to 1 year for mouse resources may apply, with immediate release of mouse resources after expiry of the grace period. Mouse mutant lines will be deposited into the INFRAFRONTIER/EMMA repository for subsequent use by the scientific community. Newly developed mouse models will be owned by the production centres and will be distributed by the INFRAFRONTIER/EMMA repository using their institutional MTAs. · Costs: The access to the INFRAFRONTIER2020 model development service is free of charge. However, the shipment cost of the newly developed mouse models must be borne by the applicants. · Eligibility: The INFRAFRONTIER2020 Trans-national Access call is open and proposals can be submitted from applicants around the world. Ten projects must be allocated to applicants from EU Member States and Associated Countries, and two projects can be allocated to applicants from third countries. · Application: Service requests for the INFRAFRONTIER2020 model development service can be made via an application form<https://www.infrafrontier.eu/resources-and-services/infrafrontier-open-call…>. Applications for the Trans-national Access activity must include a short description of the research plans for utilising the newly developed mouse model that is being generated by the INFRAFRONTIER2020 TA service. · Selection procedure: Proposals from eligible customers for free of charge access to the INFRAFRONTIER2020 mouse model development service will be subject to a review procedure. The review will be based on short descriptions of the projects involving the mouse mutants that will be produced by the TA service. A mixed panel of members of INFRAFRONTIER and of an external Evaluation Committee will assess service requests supported by the TA activity. In addition to scientific merit of applicants, soundness of the proposal and research plans, and the beneficial impact of the proposed novel mouse line on the wider biomedical research community will be assessed. Applicants will be informed on the outcome of the evaluation within 6 weeks after the end of the call for which the TA application was submitted. All applications will be handled with strict confidentiality. · Acknowledgements: Please do acknowledge any support under this scheme in all resulting publications with "Part of this work has been funded by the European Union Research and Innovation programme Horizon 2020 (Grant Agreement Number 730879). The participating infrastructure which provided the service should be specifically mentioned in any publication resulting from the service. INFRAFRONTIER - the European research infrastructure for the generation, phenotyping, archiving and distribution of mammalian models https://www.infrafrontier.eu If you do not wish to receive any further communications or wish to unsubscribe, please follow this link INFRAFRONTIER newsletter form<https://www.infrafrontier.eu/infrafrontier-newsletter/> © INFRAFRONTIER 2019 - all rights reserved

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AoF FIRI
by Emma Pirilä 21 Jan '19

21 Jan '19

Dear researchers, For those of you who have plans to apply in the Academy of Finland Research Infrastructures (FIRI) call, please find information about the university guidelines and internal deadlines. The AoF requests the universities to make an internal priorisation list and that must be done prior to the AoF deadline. Info in Finnish<https://notio.oulu.fi/fi/Lists/Tiedotteet/DispForm.aspx?ID=710> Info in English<https://notio.oulu.fi/en/Lists/Bulletins/DispForm.aspx?ID=454> Please don't hesitate to contact me should you have questions. Best regards, Emma ************************ Emma Pirilä, PhD Research Funding Specialist Faculty of Medicine Faculty of Biochemistry and Molecular Medicine Biocenter Oulu Aapistie 5A, 2nd floor FIN- 90230 University of Oulu Finland Phone: +358503426428 e-mail: emma.pirila(a)oulu.fi<mailto:emma.pirila@oulu.fi> ************************

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CRC palaveri 23.1.2019 / CRC meeting 23.1.2019
by Antti Haapalainen 21 Jan '19

21 Jan '19

Hei, Pidetään CRC:n palaveri 23.1. klo 8:30 alkaen. Käsiteltävät asiat on mainittu liitteessä. Pidämme palaverin suomeksi. Kirjoitan kokouksesta muistion myös englanniksi, jonka lähetän suomea ei-puhuville. Hi, We will have our next CRC meeting on Wednesday (Jan23) at 8:30 am. The meeting is in Finnish. However, I will prepare a memo of the meeting in English and send it to those who does not speak/understand Finnish. Terveisin, Antti Haapalainen

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Reminder! 3R-seminar: Study design 31.1.2019 - registration closes this Wednesday, 23. January
by Mirja Peltola 21 Jan '19

21 Jan '19

Reminder A seminar for researchers using experimental animals and for the students of the Health and Biosciences Doctoral Programme Dear all, The Animal Welfare Body of Laboratory Animal Centre, together with the Health and Biosciences Doctoral Programme, University of Oulu Graduate School, arranges a 3R-seminar on study design. (Programme attached) The seminar takes place on Thursday, 31st January 2019, at 8:30 - 15:45, in lecture hall 101A of the medical faculty main building, Leena Palotie -sali. Registration for attending the seminar on the spot: https://www.webropolsurveys.com/S/120EC695C2556024.par NB! The registration closes on Wednesday, 23.1.2019. The seminar is directed primarily to researchers using laboratory animals in experiments, the scientific fields therefore including basic biomedical research and preclinical medical research. However, part of the presentations are addressed to human health sciences researchers as well. Presentations that are more specific to animal studies will also include many aspects that are useful and important even for researchers of other scientific disciplines. Presentation topics and speakers: - PREPARE before you ARRIVE: planning and reporting animal experiments. Adrian Smith, Norecopa, Norway - Embracing variation to improve replicability of in-vivo research. Natasha Karp, AstraZeneca, UK - Unstable p values are causing lack of repeatability in animal experiments. Lewis Halsey, University of Roehampton, UK - Sleep and Circadian rhythms in research: Why should we care? Henna-Kaisa Wigren, University of Helsinki, Finland - Unconscious bias in scientific research - Cautionary tales from psychology's replication crisis. Stuart Ritchie, King's College, UK - Sex bias in pre-clinical research. Natasha Karp, AstraZeneca, UK The event can be considered part of the statutory maintenance of the professional competence for people working with laboratory animals. Attending the seminar gives 0,3 ECTS credits. Best regards, Sakari Sakari Laaksonen Veterinarian University of Oulu, Laboratory Animal Centre Postal address: PO Box 5000, 90014 University of Oulu, Finland Tel: +358 29 448 5097

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Kaikille avoimia tiedetapahtumia
by Meri Rova 21 Jan '19

21 Jan '19

Tervehdys! Tiedoksenne alla ajankohtaisia ja kaikille avoimia tiedetapahtumia. The public science events mentioned below are all in Finnish but everyone is welcome to join: Tietomaan Tiedebrunssit starttaavat ensi sunnuntaina. Brunsseilla Oulun yliopiston tutkijat pitävät yleistajuisia esityksiä tutkimusaiheistaan. Ensimmäisellä brunssilla, sunnuntaina 27.1., Tiina Ikäheimo Ympäristöterveyden ja keuhkosairauksien tutkimuskeskuksesta (CERH) luennoi aiheesta Kylmän vaikutuksia ihmisen terveyteen. Tutustu tiedebrunssien ohjelmaan Tiedekeskus Luupin sivuilla<https://www.ouka.fi/oulu/luuppi/tapahtumat/-/asset_publisher/dB7QbNRqmoFA/c…>. Tieteen päivät Oulussa pidetään 8.-9.2. teemalla rohkeus. Tapahtumapaikkana on Oulun Teatteri. Päivien monipuolinen ohjelma rakentuu ajankohtaisista keskusteluista ja puheenvuoroista sekä tutkijoiden tiiviistä tiede-esityksistä ja kiehtovista matkakertomuksista. Tervetuloa osallistumaan kaikille avoimeen tapahtumaan lauantaina 9.2.! Tutustu ohjelmaan Oulun yliopiston sivuilla.<https://www.oulu.fi/yliopisto/tieteenpaivat2019> Tiede vaikuttaa! -kampanja Twitterissä: Suomen yliopistojen rehtorineuvosto UNIFI ja Tutkimuslaitosten yhteenliittymä Tulanet ovat aloittaneet yhteisen Tiede vaikuttaa! -kampanjan<http://www.unifi.fi/tiede-vaikuttaa/>. Kampanjasivuilla julkaistaan talven ja kevään aikana yhteensä 13 tarinaa tieteen vaikuttavuudesta. Tarinat kertovat, miten yliopistojen ja tutkimuslaitosten tekemä tutkimus vaikuttaa meidän kaikkien elämäämme. Tarinasarjan aloitti Oulun yliopiston Pohjois-Suomen syntymäkohorttitutkimuksesta kertova artikkeli<http://www.unifi.fi/tiede-vaikuttaa/syntymakohortit/>. Seuraa kampanjaa Twitterissä tunnisteella #tiedevaikuttaa. Muistakaa myös LTK:n professoriluennot 24.1. Leena Palotie -salissa klo 13.00 alkavassa tilaisuudessa luennoivat työelämäprofessorit. Lisätietoa: https://www.oulu.fi/ltk/node/56649 Meri Rova Viestintäasiantuntija FT, Oulun yliopisto University Communications, University of Oulu Mobile phone +358-(0)50 464 3361 E-mail: meri.rova(at)oulu.fi Street address: Aapistie 5A, FI-90220 Oulu, Finland p.s. Olen opintovapaalla viikot 5-8. Tuona aikana lähettäkää kaikki palvelupyynnöt viestinnän osoitteeseen: viestinta(a)oulu.fi<mailto:viestinta@oulu.fi> I will be out of office, on study leave, during the weeks 5-8. Please contact University Communications during that time period: viestinta(a)oulu.fi<mailto:viestinta@oulu.fi>

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FW: Kurssiohjelmasta tiedotus
by Antti Haapalainen 18 Jan '19

18 Jan '19

From: Pirkko Huhtala <pirkko.huhtala(a)oulu.fi> Sent: 18. tammikuuta 2019 12:24 To: bco(a)lists.oulu.fi; fbmm(a)lists.oulu.fi; LTK <ltk-staff(a)oulu.fi> Subject: FW: Kurssiohjelmasta tiedotus FYI From: Naukkarinen Anita <Anita.Naukkarinen(a)kuh.fi<mailto:Anita.Naukkarinen@kuh.fi>> Hei! Järjestämme immunohistokemian jatkokurssin Kuopiossa 14.-15.3.2019. Pyydän, että oheisesta ohjelmastamme tiedotettaisiin. Ystävällisin terveisin, Anita Anita Naukkarinen ylisolubiologi Kliinisen patologian osasto KYS-Kuvantamiskeskus Puijonlaaksontie 2 PL 100 70029 KYS p. 044-7113477

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FW: Kastellintutkimuskeskus henkilökunnanruokailusta
by Antti Haapalainen 18 Jan '19

18 Jan '19

From: Tiina Hurskainen <tiina.hurskainen(a)oulu.fi> Sent: 18. tammikuuta 2019 10:25 To: LTK <ltk-staff(a)oulu.fi>; fbmm(a)lists.oulu.fi; bco(a)lists.oulu.fi Subject: Kastellintutkimuskeskus henkilökunnanruokailusta TIEDOKSI: Aalto cateringin kanssa on nyt tehty (OY) sopimus tuetusta lounaasta Kastellin tutkimuskeskuksessa: - Buffetlounas 7,20 € -Keitto /salaattilounas 6,60 € Sopimushinnan saa nyt alkuvaiheessa, kun kertoo kassalla olevansa OY:n työntekijä ja näyttää henkilökortin. Jatkossa säännöllisesti ao ravintolassa ruokailevat tulevat saamaan erillisen tunnistautumiskortin. FYI: The UO has now an agreement with Aalto catering in Kastellin tutkimuskeskus. - buffet lunch 7,20 e - salad/soup 6,60 e The UO employee gets the price by showing one’s ID card. Later this spring, those who use the restaurant more regularly will get a special ID card. The benefit is valid from today on.

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ERA-NEURON -call: Translational Biomarkers in Brain Disorders
by Emma Pirilä 16 Jan '19

16 Jan '19

Dear researchers, the ERA-NEURON- call for Translational Biomarkers in Brain Disorders is now open. Eligible applicants are consortia with 3-5 partners from the eligible countries. This is a 2-stage call and the deadline for 1st stage proposals is 11.3.2019. Research proposals should cover at least one of the following areas: a) Fundamental research addressing the discovery and validation of biomarkers to be used as bio signatures of the pathophysiology associated to specific neurological and psychiatric diseases. b) Clinical research on clinically relevant biomarkers for the diagnosis, patient stratification, prognosis or monitoring or prediction of treatment response and side effects for specific neurological and psychiatric diseases. The call is facilitated by the Academy of Finland. For more information, the call text etc: https://www.neuron-eranet.eu/en/865.php Please let me know if you intend to apply in this call. With best regards, Emma ************************ Emma Pirilä, PhD Research Funding Specialist Faculty of Medicine Faculty of Biochemistry and Molecular Medicine Biocenter Oulu Aapistie 5A, 2nd floor FIN- 90230 University of Oulu Finland Phone: +358503426428 e-mail: emma.pirila(a)oulu.fi<mailto:emma.pirila@oulu.fi> ************************

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FW: Kemialliset ja biologiset riskit sekä ASA vuodelta 2018
by Antti Haapalainen 16 Jan '19

16 Jan '19

Hei, Muistutuksena vielä, että 18.1. mennessä pitäisi kaikkien CRC:llä työskentelevien tehdä kemiallisten ja biologisten riskien arvioinnit mukaan lukien ASA aineet (vuosi 2018). Muutama lisäys aikaisempiin viesteihini: 1. Ilmoittakaa minulle, jos kuulutte johonkin alla mainittuun ryhmään: a. Käsittelette riskiä aiheuttavaa kemikaalia 2 tuntia tai enemmän per päivä vähintään 20 päivää per vuosi, ilmoita kemikaali b. Riskin suuruus kohtalainen tai sitä isompi (katso liite ”Henkilökohtainen riskienarviointi 3”), ilmoita kemikaali c. Työskentelette koe-eläinten kanssa säännöllisesti tai aloitatte koe-eläin työskentelyn d. Käsittelette ihmiskudoksia tai ruumiinnesteitä e. Käsittelette koe-eläinten kudoksia 2. Ilmoittakaa minulle ASA-aine, määrä (ml) per vuosi ja liuoksen pitoisuus (%). Vuonna 2017 ASA-aineita ovat olleet kloroformi, akryyliamidi ja trypan blue Säilyttäkää kemialliset ja biologiset riskiarvioinnit toistaiseksi itsellänne. Terv. Antti Haapalainen From: Antti Haapalainen Sent: 4. tammikuuta 2019 14:14 To: 'crc(a)lists.oulu.fi' <crc(a)lists.oulu.fi> Subject: FW: Kemialliset ja biologiset riskit sekä ASA vuodelta 2018 Hei, Tarkennus aikaisemmin lähettämääni viestiin. Jokaisen CRC:llä työskentelevän on tehtävä vuosittain henkilökohtaiset arvioinnit kemiallisten ja biologisten riskien suhteen mukaan lukien syöpävaaralliset aineet (ASA). Nyt on siis aika tehdä arvioinnit vuodelta 2018. Tämän lisäksi ne, jotka ovat työsuhteessa yliopistoon saatetaan kutsua lakisääteisiin terveystarkastuksiin Terveystalolle arviointien perusteella. Terv. Antti Haapalainen From: Antti Haapalainen Sent: 3. tammikuuta 2019 15:58 To: 'crc(a)lists.oulu.fi' <crc(a)lists.oulu.fi<mailto:crc@lists.oulu.fi>> Subject: Kemialliset ja biologiset riskit sekä ASA vuodelta 2018 Hei, Nyt olisi aika tehdä henkilökohtaiset arvioinnit kemiallisten ja biologisten riskien suhteen mukaan lukien syöpävaaralliset aineet (ASA). Tällä kertaa kiinnitämme erityisesti huomiota siihen, että ketkä työntekijät kutsutaan lakisääteisiin terveystarkastuksiin arviointien perusteella. Kemiallisten riskien ja biologisten vaarojen arviointiohjeet sekä malli täytettävästä riskienarviointilomakkeesta löytyvät liitteen ”Lakisääteiset terveystarkastukset” viimeiseltä dialta. Dian linkit toimivat ainoastaan silloin kun diaesitys (slide show) on päällä. Altistuksen suuruuden ja todennäköisyyden arvioinnissa voi käyttää apuna myös liitettä ”CRC_KemiallinenRiskinarviointiselvitys”. Säilyttäkää nämä arvioinnit itsellänne mutta ilmoittakaa minulle viimeistään 18.1., jos mielestänne täytätte seuraavat kriteerit: ‒ henkilö työskentelee enemmän kuin 20 pvä/vuosi suurimman osan työpäivästä tehtävissä, joissa käsitellään riskiä aiheuttavia kemikaaleja, esim. ksyleeni, akrylaatit, sytostaatit, aldehydit (mm. formaldehydi, glutaraldehydi) ‒ työskentelee herkistävien altisteiden kanssa säännöllisesti (esim. entsyymit, mm. kollagenaasi) ‒ kemiallinen riski määräytyy henkilökohtaisen riskienarvioinnin perusteella (Oulun yliopiston ohje). Jos riskin suuruus arvioidaan 3:ksi (kohtalainen riski) tai sitä isommaksi, pitäisi arvioida lakisääteisten määräaikaistarkastusten tarpeellisuutta ‒ työskentelee biologisten altisteiden kanssa säännöllisesti (esim. eläinepiteeli). Alkutarkastus ja tarvittavat rokotteet ennen töiden aloittamista. ‒ biologinen riski määräytyy henkilökohtaisen riskienarvioinnin perusteella (Oulun yliopiston ohje). Jos riskin suuruus arvioidaan 3:ksi (kohtalainen riski) tai sitä isommaksi, pitäisi arvioida lakisääteisten määräaikaistarkastusten tarpeellisuutta ‒ Työskentelee ionisoivan säteilyn kanssa. Työntekijät jaetaan kahteen luokkaan A ja B. B-luokkaan (alle 6 mSi/v) kuuluvat työntekijät käyvät alkutarkastuksessa. A-luokkaan kuuluvat (yli 6 mSi/v) käyvät alkutarkastuksessa ja määräaikaistarkastuksissa kolmen vuoden välein. Vuonna 2017 CRC:llä käytettiin seuraavia ASA-aineita: kloroformi, akryyliamidi ja trypan blue. Ne, jotka ovat käyttäneet näitä ASA-aineita vuonna 2018, ilmoittakaa minulle aine, määrä (ml) per vuosi ja liuoksen pitoisuus (%). Ilmoittakaa, jos olette käyttäneet jotain muuta ASA-ainetta (liite ”syopasairauden-vaaraa-aiheuttavat-tekijat”). Ilmoittakaa nämäkin minulle viimeistään 18.1. Jos on epäselvyyttä jonkin asian suhteen, tulkaa ihmeessä kysymään. Terv. Antti Haapalainen (366B)

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Crc January 2019