Crc August 2022

crc@lists.oulu.fi

11 participants
51 discussions

Seminar: Obesity and Fibrosis at the Crossroads of Human Health and Disease - see the final programme and book your seat!
by Essi Erkkilä 24 Aug '22

24 Aug '22

Dear all, Everyone is welcome to the Joint Seminar<https://www.oulu.fi/en/events/seminar-obesity-and-fibrosis-crossroads-human…> of the Finnish Association for the Study of Obesity (FASO) and Fibrobesity Research Programme on 13 October 2022. See below the final programme. The event is hybrid and has no registration fees. If you didn't submit an early-bird registration, book your seat now! Event information Time: Thu 13.10.2022 at 08:30 - 16:15 Location: Leena Palotie Hall and online via Zoom Registration: Please register by October 10<https://link.webropolsurveys.com/Participation/Public/8310ae8c-8d21-4067-a2…>. No registration fee. Please note that regardless of the type of participation (on-site or remote) pre-registration is required. [A picture containing text Description automatically generated] Programme 8:30-9:00 Coffee at the lobby (provided) 9:00-9:10 Opening words: Prof. Janne Hukkanen, FASO Vice-Chair, and Prof. Olavi Ukkola, Profi6 Fibrobesity Leader 9:10-11:25 Clinical aspects of fibrosis and obesity Prof. Juhani Junttila, UO: Obesity and Fibrosis in Myocardial Disease Prof. Riitta Kaarteenaho, UO: Pulmonary Fibrosis and Obesity Break (10 min at 10:00-10:10) Associate Prof. Daniela Ungureanu, UO: Obesity and Cancer at the Molecular Level Prof. Janne Hukkanen, UO: Obesity-Induced Hypertension and Sex-Specific Blood Pressure Regulation Prof. Terhi Piltonen, UO: Sex Hormones and Fibrosis 11:25-12:25 Lunch break (at own expenses) 12:25-13:10 Keynote talk Associate Prof. Mari T. Kaartinen, McGill University, Montreal, Canada: Coagulation Factor XIII-A in Adipose Tissue Inflammation and Fibrosis in Obesity 13:10-14:25 Molecular and cellular characteristics of fibrosis and obesity Prof. Jukka Hakkola, UO: Pregnane X Receptor Activation Remodels Liver Metabolism to Promote NAFLD Development in Obese Mice Prof. Peppi Karppinen, UO: Activation of the HIF Pathway as a Treatment Option for Metabolic Dysfunction Adjunct Prof. Justus Reunanen, UO: Metabolic Features of Gut Extracellular Vesicles in Bariatric Surgery Patients 14:25-14:45 Coffee break 20 min (provided) 14:45-16:00 Exercise and urban planning in the prevention of obesity Associate Prof. Arto Hautala, University of Jyväskylä: Individual Responses to Exercise Training Ph.D. Mikko Kärmeniemi, UO: The Built Environment as a Determinant of Physical Activity Prof. Helka-Liisa Hentilä, UO: Urban Planning for Enhancement of Physical Activity: What needs to be changed? 16:00-16:15 Wrap-up and closing words by Prof. Janne Hukkanen Welcome to the Seminar<https://www.oulu.fi/en/events/seminar-obesity-and-fibrosis-crossroads-human…>! On behalf of the Fibrobesity Team, Essi Erkkilä --------------------------------------------------------------------------------------- Essi Erkkilä Communications Specialist, Profi6 Fibrobesity Research Unit for Internal Medicine (Room S5 224) Faculty of Medicine University of Oulu tel. +358 50 521 5852 Twitter: FibroHealthOulu @FibroOulu FibroHealth - Combatting Fibrosis in Chronic Diseases | University of Oulu<https://www.oulu.fi/en/fibrohealth-combatting-fibrosis-chronic-diseases> [cid:image002.jpg@01D8B7C0.76C6BF10]

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REMINDER: Open online lecture, QUPATH: OPEN-SOURCE SOFTWARE FOR BIOIMAGE ANALYSIS AND DIGITAL PATHOLOGY, August 25th at 1 PM
by Sanna Palosaari 24 Aug '22

24 Aug '22

August 25th 13:00 Finnish time Open online lecture: https://oulu.zoom.us/j/64556587648 QuPath: Open-source software for bioimage analysis and digital pathology Reader, Peter Bankhead Institute of Genetics and Cancer University of Edinburgh [cid:image001.jpg@01D8B79C.C9F24A70] Dr Peter Bankhead - Reader Realising the potential of image analysis and AI for biology and pathology is hard, and requires software. Firstly, we need open and adaptable software tools that help specialists in different areas work together to devise meaningful algorithms. We then need user-friendly and accessible software platforms to make these algorithms widely available, so that others can validate and apply them in practice. QuPath (http://qupath.github.io) is free and open-source software designed to help address these needs. Since its release in 2016, QuPath has been downloaded more than 240,000 times and applied in well over 1,000 published studies by groups throughout the world. A growing community of users and developers are now using the platform to create innovative ways of exploring complex biomedical images, with over 2,300 QuPath-related discussions on the Scientific Community Image Forum at https://image.sc. This talk will describe QuPath’s background and current status, what the future holds, and how the software can be useful for a wide range of different groups working with whole slide and microscopy images today. Bio Pete completed his PhD at Queen’s University Belfast, focussing on the analysis of retinal images and calcium signals in retinal arterioles. He then moved to Germany, becoming a postdoc in the Nikon Imaging Center at Heidelberg University where he spent much of his time helping microscope users interpret their imaging data using open-source software. During this time he wrote a bioimage analysis handbook for biologists. This has recently been rewritten and released as a new open, interactive, executable book at https://bioimagebook.github.io. Upon returning to Belfast as a postdoc at the end of 2012, Pete encountered digital pathology for the first time. After trying to apply existing open software tools to whole slide images with limited success, he wrote his own: QuPath. After a short time in industry, Peter is now Reader (Associate Professor) at the University of Edinburgh, where he is building a group dedicated to developing open AI and bioimage analysis methods for pathology and other imaging data. Welcome to join and please feel free to share with colleagues.

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Canceled: LTK:n henkilöstöinfo / Staff Info at the Faculty of Medicine
by Jaana Liimatainen 23 Aug '22

23 Aug '22

Oulun yliopiston hallitus on tänään käsitellyt Lääketieteellisen tiedekunnan talouden tasapainottamissuunnitelmaa. Hallitus ei tehnyt asiasta päätöstä, vaan päätti jatkaa asian käsittelyä. Tasapainottamissuunnitelmasta ei siten ole uutta tiedotettavaa, joten tämä LTK:n henkilöstöinfo siirretään myöhemmin ilmoitettavaan ajankohtaan. The Board of Directors at the University of Oulu decided today to continue discussing the measures to balance the financial situation of the Faculty of Medicine in a later meeting. As there is no new information to report, this Staff Info at the Faculty of Medicine will be postponed. The new date will be announced later. Dekaani/Dean Osmo Tervonen Tervetuloa LTK:n henkilöstöinfoon / Welcome to the Staff Info at the Faculty of Medicine Aihe: Tiedekunnan talouden tasapainottaminen Paikka: Leena Palotie -sali 101A ja Teams Aika: 24.8. klo 14.00-14.30 suomeksi Topic: Balancing the financial situation of the faculty Location: Leena Palotie auditorium 101A and Teams Date: 24th of August at 14.30-15.00 in English Dekaani/Dean Osmo Tervonen ________________________________________________________________________________ Microsoft Teams meeting Join on your computer or mobile app Click here to join the meeting<https://teams.microsoft.com/l/meetup-join/19%3ameeting_NWYxZjFjODktZmNhNi00…> Meeting ID: 363 774 402 397 Passcode: Kik69o Download Teams<https://www.microsoft.com/en-us/microsoft-teams/download-app> | Join on the web<https://www.microsoft.com/microsoft-teams/join-a-meeting> Or call in (audio only) +358 9 85626307,,601620882#<tel:+358985626307,,601620882#> Finland, Helsinki Phone Conference ID: 601 620 882# Find a local number<https://dialin.teams.microsoft.com/3842a853-a94d-4f5e-b81d-3786eed9ea69?id=…> | Reset PIN<https://dialin.teams.microsoft.com/usp/pstnconferencing> Learn More<https://aka.ms/JoinTeamsMeeting> | Meeting options<https://teams.microsoft.com/meetingOptions/?organizerId=b837850c-0d5e-491c-…> ________________________________________________________________________________

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Tyytyväisyyskysely – Tutkimuspalvelut
by Tutkimuspalvelut 23 Aug '22

23 Aug '22

Uudistuneet Tutkimuspalvelut – oletko tyytyväinen? Tutkimuspalvelut uudistettiin organisaatiouudistuksen yhteydessä ja hajallaan olevat resurssit koottiin yhteen laadun, vaikuttavuuden ja tuottavuuden parantamiseksi. Uudistuneissa tutkimuspalveluissa hoidetaan nyt keskitetysti tutkimuslupaprosessi, tutkimussopimukset, taloushallinto, henkilöstöhallinto, tilastotieteen palvelut ja tutkimusten monitorointi. Haluaisimme nyt tietää oletko ollut tyytyväinen uudistukseen ja palveluihimme? Kyselyyn vastaaminen tapahtuu anonyymisti eikä vastaajien henkilöllisyyttä voi tunnistaa. Linkki kyselyyn: https://link.webropolsurveys.com/S/6F39B09A913489DF Toivoisimme sinun vastaavaan kyselyyn 16.9.2022 mennessä. Yhteistyöterveisin Tutkimuspalvelut

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juttukakkua
by Jussi Tuusa 23 Aug '22

23 Aug '22

Hei, kahvihuoneessa tarjolla kakkua hyväksytyn jutun innoittamana. Jussi

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FW: Kliinisen lääketieteen tutkimusyksikön tutkijankoulutuskurssi (ent. PEDEGO-tutkijakoulutus) - ilmoittautuminen avoinna kaikille Oulun yliopistossa kliinistä väitöskirjaa tekeville tutkijoille
by Antti Haapalainen 22 Aug '22

22 Aug '22

From: Eero Kajantie <Eero.Kajantie(a)oulu.fi> Sent: torstai 18. elokuuta 2022 20.54 To: LTK <ltk-staff(a)oulu.fi>; ltk-students(a)oulu.fi Subject: VL: Kliinisen lääketieteen tutkimusyksikön tutkijankoulutuskurssi (ent. PEDEGO-tutkijakoulutus) - ilmoittautuminen avoinna kaikille Oulun yliopistossa kliinistä väitöskirjaa tekeville tutkijoille ________________________________ Hyvät lääketieteellisen tiedekunnan väitöskirjatutkijat, ohjaajat ja muu tutkimusyhteisö, kliinisen lääketieteen tutkimusyksikkö järjestää kaksivuotisen tutkijankoulutuskurssin, joka on suunnattu erityisesti kliinistä väitöskirjaa tekeville tutkijakoulutettaville. Koulutuksen toisen vuoden ilmoittautuminen avautuu nyt kaikille Oulun yliopiston tutkijakoulutettaville (ilmoittautumisessa on tähän asti ollut etuoikeus kurssin ensimmäisen vuoden käyneillä). Kurssin ohjelma on liitteenä. Koska ilmoittautumismahdollisuus alkaa melko myöhään (ensimmäisen opetuskerran jälkeen), tämä huomioidaan kurssin läsnäolovaatimuksissa. Ilmoittautuminen on Pepissä opintojaksotunnuksella 046037J tai 046037J-3001. Opintojaksolle otetaan enintään 30 henkeä ilmoittautumisjärjestyksessä. Pyytäisimme myös ohjaajia ja tutkijakollegoita vihjaamaan kurssista mahdollisesti kiinnostuneille tutkijakoulutettaville. Ystävällisin terveisin Kurssin vastuuhenkilöt Eero Kajantie Elämänkaarilääketieteen professori Terhi Tapiainen Lastentautiopin professori

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Multiple new researcher positions are open in Profi6 Fibrobesity!
by Essi Erkkilä 18 Aug '22

18 Aug '22

Dear all, Profi6 Fibrobesity - Preventing Fibrosis Related to Obesity - is expanding! Currently, there are new open calls for four positions, which are divided as follows. [Graphical user interface Description automatically generated] Four open positions in osteoarthritis and intervertebral disc degeneration research<https://www.oulu.fi/en/news/open-positions-two-postdoctoral-and-two-doctora…> * Professor Ali Mobasheri is looking for two postdoctoral researchers and two doctoral researchers to join his research group in the Research Unit of Medical Imaging, Physics and Technology, Faculty of Medicine. * Postdoctoral researcher in Musculoskeletal Research<https://rekry.saima.fi/certiahome/open_job_view.html?did=5600&lang=en&id=00…> and Doctoral researcher, Faculty of Medicine<https://rekry.saima.fi/certiahome/open_job_view.html?did=5600&lang=en&id=00…>: These two positions are targeted to a project focused on understanding pathogenic mechanisms in osteoarthritis and intervertebral disc degeneration, identifying biomarkers, and developing next-generation biological therapeutics for these diseases. Call deadline: September 18, 2022. * Postdoctoral Researcher in Intervertebral Disc Experimental Therapeutics<https://rekry.saima.fi/certiahome/open_job_view.html?did=5600&jc=1&id=00001…> and Doctoral Researcher in Intervertebral Disc Experimental Therapeutics<https://rekry.saima.fi/certiahome/open_job_view.html?did=5600&jc=1&id=00001…>: Additional two positions are open on an interdisciplinary project focused on the formulation and testing of experimental therapeutics for the treatment of intervertebral disc degeneration and low back pain, including nanotechnology, senolytics, and cell-based gene therapy. Call deadline: September 30, 2022 On behalf of the Fibrobesity Team, Essi Erkkilä --------------------------------------------------------------------------------------- Essi Erkkilä Communications Specialist, Profi6 Fibrobesity Research Unit for Internal Medicine (Room S5 224) Faculty of Medicine University of Oulu tel. +358 50 521 5852 Twitter: FibroHealthOulu @FibroOulu FibroHealth - Combatting Fibrosis in Chronic Diseases | University of Oulu<https://www.oulu.fi/en/fibrohealth-combatting-fibrosis-chronic-diseases> [cid:image002.jpg@01D8B309.1AA506D0]

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FW: LTK:n henkilöstöinfo / Staff Info at the Faculty of Medicine
by Antti Haapalainen 17 Aug '22

17 Aug '22

-----Original Appointment----- From: Jaana Liimatainen <jaana.liimatainen(a)oulu.fi<mailto:jaana.liimatainen@oulu.fi>> Sent: keskiviikko 17. elokuuta 2022 8.34 To: Jaana Liimatainen; LTK; LTK-idm Subject: LTK:n henkilöstöinfo / Staff Info at the Faculty of Medicine When: keskiviikko 24. elokuuta 2022 14.00-15.00 (UTC+02:00) Helsinki, Kyiv, Riga, Sofia, Tallinn, Vilnius. Where: Leena Palotie -sali 101A ja Teams (linkki kutsutekstissä) Tervetuloa LTK:n henkilöstöinfoon / Welcome to the Staff Info at the Faculty of Medicine Aihe: Tiedekunnan talouden tasapainottaminen Paikka: Leena Palotie -sali 101A ja Teams Aika: 24.8. klo 14.00-14.30 suomeksi Topic: Balancing the financial situation of the faculty Location: Leena Palotie auditorium 101A and Teams Date: 24th of August at 14.30-15.00 in English Dekaani/Dean Osmo Tervonen ________________________________________________________________________________ Microsoft Teams meeting Join on your computer or mobile app Click here to join the meeting<https://teams.microsoft.com/l/meetup-join/19%3ameeting_NWYxZjFjODktZmNhNi00…> Meeting ID: 363 774 402 397 Passcode: Kik69o Download Teams<https://www.microsoft.com/en-us/microsoft-teams/download-app> | Join on the web<https://www.microsoft.com/microsoft-teams/join-a-meeting> Or call in (audio only) +358 9 85626307,,601620882#<tel:+358985626307,,601620882#> Finland, Helsinki Phone Conference ID: 601 620 882# Find a local number<https://dialin.teams.microsoft.com/3842a853-a94d-4f5e-b81d-3786eed9ea69?id=…> | Reset PIN<https://dialin.teams.microsoft.com/usp/pstnconferencing> Learn More<https://aka.ms/JoinTeamsMeeting> | Meeting options<https://teams.microsoft.com/meetingOptions/?organizerId=b837850c-0d5e-491c-…> ________________________________________________________________________________

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FW: Tiedote/Information
by Antti Haapalainen 16 Aug '22

16 Aug '22

From: Osmo Tervonen <osmo.tervonen(a)oulu.fi> Sent: tiistai 16. elokuuta 2022 12.20 To: LTK <ltk-staff(a)oulu.fi> Subject: Tiedote/Information Hei Tiedekunnan talous on ollut esillä alkuvuonna mm henkilöstöinfoissa. Vuoden 2022 taloussuunnitelma on tehty sillä ajatuksella, että lisääntyvä täydentävä rahoitus tasapainottaa alijäämän. Nyt on seurattu tilannetta puoli vuotta, ja näyttää siltä, että talous ei oikene, alijäämä ylittää taseessa olevan liikkumavaran. Olen menossa yliopiston hallituksen kokoukseen tiistaina 22.8., jossa on tarkoitus päättää jatkotoimenpiteistä. Alla on käsittelyyn liittyvä virallinen tiedote. Pidetään seuraava henkilöinfo keskiviikkona 23.8. hallituksen kokouksen jälkeen, jolloin tiedämme miten jatketaan. Tästä tulee myöhemmin kutsu; tapaaminen on sekä ns paikan päällä ja etänä. Osmo Tervonen Dekaani Hi The financial situation in the Medical Faculty has been a topic which has been discussed in e.g. personnel information meetings. The financial plan for the year 2022 has been made with the idea that increasing additional fiundng will balance the deficit. We have been following the situation now for half the year now, and it seems that the situation is not correcting. I will go to the meeting of the university's board on Tuesday, August 22, which we will define the further actions. Below is the official announcement related to the process. I will have the next personnel information meeting on Wednesday 23.8. the day after the university board meeting, and then we know how to proceed. There will later be an invitation; the meeting is both on-site and remotely. Osmo Tervonen Dean Lääketieteellinen tiedekunta esittää toimenpiteitä taloustilanteen korjaamiseksi Lääketieteellisen tiedekunnan taloudellinen tulos on kehittynyt alkuvuoden 2022 aikana suunniteltua enemmän alijäämäiseksi. Heinäkuun loppuun mennessä alijäämää on kertynyt yli 1,2 miljoonaa euroa, ja koko vuoden ennuste on yli 1,4 miljoonaa euroa alijäämäinen. Tiedekunnan ja sen yksiköiden tuloihin ei ole odotettavissa merkittävää lisäystä loppuvuoden tai ensi vuoden aikana. Tiedekunnan taloustilanteen arvioidaan jäävän vuonna 2023 edelleen huomattavan alijäämäiseksi, ellei ryhdytä toimenpiteisiin tilanteen korjaamiseksi. Tiedekunnan laskennallisen taseen arvioidaan olevan kokonaan käytetty vuoden 2022 loppuun mennessä, joten enää vuonna 2023 alijäämää ei ole mahdollista rahoittaa tiedekunnan taseesta. Esitän yliopiston hallitukselle, että tiedekunta ryhtyy tarvittaviin toimenpiteisiin toiminnan uudelleenjärjestelyiksi sekä kustannusten alentamiseksi. Tavoitteena on alentaa kustannuksia alijäämän verran, arviolta 1,4 miljoonan euroa vuositasolla. Tavoiteltava kustannussäästö vastaa yhteensä noin 25:tä henkilötyövuotta. Uudelleenjärjestelyjen lisäksi suunnitellut toimenpiteet voivat sisältää kokoaikaisen ja osa-aikaisen henkilöstön irtisanomisia ja osa-aikaistamisia. Suunnitelluista toimenpiteistä käynnistettäisiin yhteistoimintalain mukaiset muutosneuvottelut. Yliopiston johtosäännön mukaan dekaanin tehtävänä on johtaa tiedekunnan toimintaa ja vastata tiedekunnan tehtävien taloudellisesta, tehokkaasta ja tuloksellisesta hoitamisesta. Yliopiston hallitus päättää asiasta kokouksessaan 23.8.2022. Tiedekunnan henkilöstölle ja opiskelijaedustajille järjestetään asiasta infotilaisuus kokouksen jälkeen. Faculty of Medicine suggests measures to remedy the economic situation The deficit of the Faculty of Medicine has grown more than planned in early 2022. By the end of July, the deficit has accumulated to more than EUR 1.2 million and the forecast for the full year is over 1.4 million euros in deficit. No significant increase in income for faculty and its units is expected for the rest of the year or next year. The financial situation of the faculty is projected to remain in considerable deficit in 2023 unless measures are taken to remedy this situation. The computational balance of the faculty is estimated to be fully used by the end of 2022, so it will not be possible to finance the deficit in 2023 from the faculty balance sheet. I present to the University Board of Directors that the faculty will take the necessary measures to restructure operations as well as to reduce costs. The aim is to reduce costs as much as the deficit is, estimated at an annual rate of EUR 1.4 million. The cost savings to be pursued corresponds to a total of about 25 person-years. In addition to restructuring, planned measures may include redundancies and part-time full-time and part-time staff. Change negotiations under the Act on Co-operation would be launched on the planned measures. According to the University Regulations, the Dean's role is to lead the activities of the faculty and to be responsible for the financial, efficient and effective discharge of the faculty's functions. The University Board of Directors will decide on this matter at its meeting on 23 August 2022. An information session will be held for faculty staff and student representatives after the meeting.

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Three Fibrobesity postdoc positions 2023-25
by Ritva Saastamoinen 15 Aug '22

15 Aug '22

Hi, Profi6 Fibrobesity recruitment programme continues! We are looking for motivated postdocs to strengthen our sub-themes Fibro1, 2 and 3. Deadline is on September 20. The positions are planned to be filled for 2023-25. This call offers also an excellent opportunity for our PIs to recruit new research group members with the support of Profi funding. Feel free to advertise the positions in your networks to find potential candidates! See the call announcement below for details. Link to online application: Avoin työpaikka (saima.fi)<https://rekry.saima.fi/certiahome/open_job_view.html?did=5600&jc=1&id=00001…> We are now seeking talented scientists for Three postdoctoral positions in FIBROBESITY – Preventing Fibrosis Related to Obesity to strengthen our research focusing on obesity-related fibrotic pathologies. Open postdoctoral positions are available in FIBROBESITY for 2023-25. The duration of the fixed term is three years. Research theme FIBROBESITY – Preventing Fibrosis Related to Obesity - is one of the three multidisciplinary research programmes supported by the Academy of Finland PROFI6 funding during 2021-2026. FIBROBESITY links strongly with the strategy of the University of Oulu (UO) under a wider umbrella of FibroHealth – Combatting Fibrosis in Chronic Diseases. While FibroHealth at large addresses fibrosis, which is a risk factor in the etiology of complex chronic diseases and unhealthy ageing, FIBROBESITY focuses on medical and societal challenges of obesity-related fibrotic pathologies. Our research draws on strong multidisciplinary expertise integrating biomedical sciences, ICT and human sciences. FIBROBESITY represents mainly the UO research focus area “Lifelong Health” and links with “Understanding humans in change” and “Digitalization and smart society”, thus building bridges between researchers in several faculties. The world-class research at UO on hypoxia and extracellular matrix (ECM) together with cutting-edge research on obesity, cardiovascular risk factors, metabolic syndrome, polycystic ovary syndrome and other fibrosis-related diseases, combined with our unique population and patient cohort studies and state-of-the art research infrastructure (https://www.oulu.fi/en/research/research-infrastructures) form the basis of FIBROBESITY. The pressing issues addressed by FIBROBESITY relate to its three sub-themes as follows. Molecular Mechanisms and Clinical Significance of Fibrosis (FIBRO1) strives to identify currently poorly known molecular pathways causative for obesity and fibrosis. Disease Modelling for Future Therapies (FIBRO2) facilitates translational studies through development of novel in vitro and in vivo disease models. Societal and Behavioural Perspectives (FIBRO3) combines approaches at a broader range of disciplines to reveal lifelong behavioural determinants of obesity. Relevant links: https://www.oulu.fi/en/research/combatting-fibrosis-chronic-diseases, https://www.oulu.fi/en/research What we expect and job description We are seeking motivated scientists for all three above-described sub-themes FIBRO1, 2 and 3. A successful applicant can thus have a background in a wide range of scientific disciplines and is expected to have competence and planned or already ongoing research in at least one of the following areas linked to obesity and obesity-related fibrosis: - Epidemiology or genetics - Clinical studies - Molecular and cellular mechanisms - Model organisms and disease modelling for future therapies - Behavioural and societal perspectives - Other relevant area fitting in the thematic scope We appreciate innovative visions for interdisciplinary and new collaborative research initiatives. The core of your research and action plan may include or relate, for example, to one or more of the following questions: - What are the molecular mechanisms connecting obesity and fibrosis, including the roles of hypoxia, ECM remodelling and inflammation? - Can we treat obesity and fibrosis-related co-morbidities by controlling those identified molecular mechanisms, such as activation of the hypoxia response, in vitro and in vivo? - What are the genetic and other risk factors leading to obesity and fibrosis-related co-morbidities in individuals and in populations? How can we identify individuals with the increased risk? - What are the mechanisms and associations of early-life exposures, lifelong risk for obesity and co-morbidities including fibrosis in selected complex chronic diseases? What are the factors predicting the extent of weight-loss in the intervention and cohort studies? - What kind of historical, socio-cultural and behavioural factors underlie obesity and related health issues? How can these insights be integrated to behavioural guidance? You may indicate ongoing or planned connections with specific researchers at the University of Oulu and identify a desired research group or research unit in the application. This is not a pre-requisite, but we would encourage the applicants to establish a connection with appropriate hosting research unit already before submitting the application. Alternatively, the applicant and the hosting research unit can also be matched during the evaluation and selection process. To be eligible, you must hold a completed doctoral degree (at or later than 2013, or max 10 years ago excluding career breaks) and carry out the planned research in a relevant field of FIBROBESITY, such as medicine, biomedicine, biochemistry, molecular biology, health science, history, psychology or other human science, or ICT. We expect ability to work independently and activity in academic community. Fluency in both written and spoken English, as well as good communication, presentation and teamwork skills are required. Demonstrated experience in local, national and international networking, history of research mobility, as well as potential in acquiring supplementary funding and teaching experience will be taken as merits. As a postdoctoral researcher, your primary duties may include: - carrying out collaborative research leading to high-quality academic publications - contribution to writing and submitting research funding proposals - activity in the academic community - supervision of MSc students or doctoral researchers - participation in teaching tasks, subject to faculty needs and your own teaching capabilities and interests (maximum of 15% of the working hours) What we offer We offer you an interesting and versatile research topic to solve globally significant research problems in an international environment and the possibility to develop professionally with the help of experienced colleagues. Furthermore, we offer you access to excellent research infrastructure equipment and services, as well as targeted Fibrobesity research programme funding opportunities. The successful candidate will be employed at UO. The salary will be based on level 5-6 of the demand level chart for university-level teaching and research staff of Finnish universities. In addition, a salary component based on personal work performance will be paid (maximum of 50 % of the job-specific component). The starting salary will be approximately €3500-4000 per month (before taxes), depending on the qualifications. Regular salary is paid 12 months per year, including paid leave and an additional holiday bonus in the summer. In addition to the salary, the employed person will be insured by the university and provided occupational healthcare. Finnish government provides benefits to residents and their families, for example possibility to the national healthcare system and high-quality affordable childcare and school services. Applications and selection process Apply online<https://rekry.saima.fi/certiahome/open_job_view.html?did=5600&lang=en&id=00…> latest on Tuesday, September 20, 2022 at 23:59 Finnish local time (EET). The application should be written in English. Please include the following documents in separate pdf files: 1. Letter of motivation with contact information (max. 2 pages) You can choose to indicate the following information: - Research interests and career plans - Professional experience and expertise - Potential hosting research unit(s), if you already are able to identify it (optional) 2. Curriculum vitae following the guidelines of the Finnish Advisory Board on Research Integrity: http://www.tenk.fi/en/template-researchers-curriculum-vitae 3. Complete list of publications, following the guidelines of the Academy of Finland: https://www.aka.fi/en/research-funding/apply-for-funding/how-to-apply-for-f…. Please mark the five most important ones. 4. Brief three-year research and action plan, including the applicant’s vision how to renovate the field of science in FIBROBESITY, with the following sections (max 3 pages, excluding bibliography): - Aim and objectives - Implementation and funding - The role of the applicant in the research project - Ethical issues Tips for writing a research plan: https://www.aka.fi/en/research-funding/apply-for-funding/how-to-apply-for-f… 5. Contact information of 2-4 potential referees who may be asked to give a statement of the candidate 6. Certificates/Diplomas: Scanned copy of the original doctoral degree certificate. Only applications containing all relevant appendices and submitted through the online recruitment system will be considered. The selection process is carried out by a recruitment committee. Eligible candidates are subjected to an evaluation. The following merits will be assessed: - Scientific level and relevance of the research and action plan - Feasibility of the research and action plan and fitting of the research interests in the thematic scope of Fibrobesity - CV, considering the applicant's career stage and discipline. Including shown potential to attract external funding and research mobility - Publications, considering the applicant's career stage and discipline - Multidisciplinarity and potential for collaboration with other profiling themes - National and international scientific contacts - Mobility plans - Societal relevance The candidates who are considered most suitable after document-based evaluation will be invited to an on-site or remote interview. All applicants will be notified when the selection process is completed. Further information and inquiries The positions are filled for a fixed-term of 3 years starting on January 2023 or as agreed. A trial period of six months is applied in the position. For informal inquiries, please contact Fibrobesity Coordinator Ritva Saastamoinen, ritva.saastamoinen(at)oulu.fi, 050 592 3333, 0294 48 5226 https://rekry.saima.fi/certiahome/open_job_view.html?did=5600&lang=en&id=00… Best wishes, Ritva --------------------------------------------------------------------------------------- Ritva Saastamoinen PhD, Adjunct Professor (Docent) Coordinator, Profi6 Fibrobesity Research Unit for Internal Medicine (Room S5 230) Faculty of Medicine University of Oulu tel. +358 294 48 5226, +358 50 592 3333 Twitter: FibroHealthOulu @FibroOulu FibroHealth - Combatting Fibrosis in Chronic Diseases | University of Oulu<https://www.oulu.fi/en/fibrohealth-combatting-fibrosis-chronic-diseases> [cid:image001.png@01D8B099.90C31AE0]

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Crc August 2022