From: Jaakko Tyrmi jaakko.tyrmi@oulu.fi Sent: Friday, October 11, 2024 10:17 AM To: ltk-all ltk-all@oulu.fi Subject: FinnGen data now includes Kanta laboratory values
Dear all,
As part of our continuous expansion of FinnGen resources for research, Kanta register data has been integrated into the FinnGen data repository. Those of you who are already utilizing FinnGen in your work may have received information regarding this update, but we are sharing it more widely as these datasets offer valuable insights and research opportunities also for those not currently using FinnGen.
The FinnGen research project has expanded its research data with laboratory results from the Kanta register. The added data include all basic laboratory tests used in medical care as well as a number of less common laboratory results. Laboratory data are available for more than 400 000 FinnGen participants. The first Kanta laboratory results are from 2014, with comprehensive results available from 2018 onwards.
FinnGen's experts carried out extensive quality control of the laboratory values before introducing the new data into FinnGen. In addition, the data have been harmonised and adapted to international standards to facilitate the straightforward use of the data in research. Combining the Kanta data with the existing genetic and health data will open up new opportunities for studying disease progression, which is one of the main research objectives of FinnGen.
Researchers can access the number of laboratory measurements and the average laboratory results per disease using Risteys. The Risteys website is a comprehensive and open application hosted by FinnGen that allows you to view non-individual-level summary results for health variables in the FinnGen data. For example, it provides information on the prevalence of different diseases in Finland by age group and the different medicines used to treat the diseases, according to the level of use. Now Risteys also provides case-by-case laboratory measurements for different diseases, which can be classified by prevalence, incidence or outcome: https://risteys.finregistry.fi
FinnGen's pseudonymised individual-level genotype, health and laboratory data can be used by researchers working for the organisations participating in the FinnGen study for the purposes of the FinnGen study. Participant organisations include University of Oulu, Oulu University Hospital and large number of others. The data can only be processed in FinnGen's audited and approved secure research environment, the Sandbox.
FinnGen is a public-private partnership involving Finnish universities, hospital districts, the Finnish Institute for Health and Welfare, Blood Service, biobanks, FINBB and several international pharmaceutical companies. FinnGen is a biobank research project that aims to understand the genetic and molecular mechanisms of many diseases by combining data from biobank samples and health registers. Read more about FinnGen: https://www.finngen.fi/en
Please let me know if you have any questions about how to apply for access to use FinnGen resources in your own research.
Best regards, Jaakko Tyrmi
--
Jaakko Tyrmi, Postdoctoral Research Fellow FinnGen local support Faculty of Medicine, University of Oulu jaakko.tyrmi@oulu.fimailto:jaakko.tyrmi@oulu.fi