Dear laboratory animal researchers

 

The use of both sexes in laboratory animal experiments has been increasingly advocated during the recent years. The Finnish 3R centre arranges a webinar on Tuesday, 14 November, with biostatistician Natasha Karp talking about sex-inclusive in vivo research. Those of you who attended our own 3R seminar in 2019 in Oulu might remember that Natasha gave talks on sex bias in research and the use of controlled variation in study design. Below you can find more information and registration link for the next Tuesday’s webinar.

 

Best regards

 

Sakari

 

Sakari Laaksonen

Designated veterinarian

Oulu Laboratory Animal Centre (OULAC)

University of Oulu, Finland

Postal address: PO Box 5000, 90014 University of Oulu, Finland

Tel: +358 294 48 5097

 

 

Fin3R Center webinar in Zoom 

November 14, 2023 at 14:00 (Helsinki, East-European Time) 

TOPIC: One sex fits all? The current thinking on sex inclusive in vivo research 

In recent years, there has been a strong drive to improve the inclusion of animals of both sex during in vivo research, driven by a need to improve sex representation in fundamental biology and drug development. This has resulted in inclusion mandates by a variety of funding bodies (e.g., NIH and MRC) and journals. This talk will dispel the common misconceptions that are no longer appropriate justification for studying only one sex. We then explore, how to build an appropriate justification to study only one sex at a case-by-case level. Finally, I will touch upon the impact of including both sexes on data analysis. 

SPEAKER: Dr. Natasha Karp (AstraZeneca, UK) 

Natasha is a Director of Statistics within AstraZeneca leading a team of statisticians supporting preclinical research.  In addition, Natasha is an active researcher publishing papers with a focus on the challenges within preclinical research with a particular interest in improving replicability, reproducibility, and generalizability of the studies.  More recently, Natasha has published meta-research articles around the process of research.  This has included qualitative research into blinding in in vivo studies, blockers to the engagement with sex inclusive research and the impact of sex inclusive research on statistical power.   

Register in advance for this meeting: 

https://helsinki.zoom.us/meeting/register/u5Uuf-msqDgiEtXgOZO7QiXKv4YuXGSa2oBr  

After registering, you will receive a confirmation email containing information about joining the meeting. 

 

Ref: https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002129

https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14539

 

 

 

_________________________________________
Vootele Voikar, MD, PhD
Neuroscience Center / Laboratory Animal Center
Helsinki Institute of Life Science (HiLIFE)
P.O. Box 29 (Mustialankatu 1G)
FI-00014 University of Helsinki
Finland

Phone: +358 2941 57658
Mobile: +358 50 416 0466
E-mail: vootele.voikar@helsinki.fi

 

https://www.fingmice.fi/mbpf/