Dear All,

Welcome to follow the presentations of the BCO groups 2024-2027. Place: Leena Palotie sali 101A, Aapistie 5A Date: Thursday 18 January 2024 starting at 9.00 until 15.45 hrs.

The registration is for the coffee service and the lecture is open to everyone. The closing date for the registration is Thursday 11.1.2024. https://link.webropolsurveys.com/S/4B01FE17A0B1E358

PROGRAMME

9.00 Morning coffee 9.30-10.00 Opening words Johannes Kettunen, Scientific director, Biocenter Oulu Lauri Eklund, Core Services director, Biocenter Oulu 10.00-10.15 Mika Ala-Korpela and Ville-Petteri Mäkinen: Innovative multi-domain metabolomics paradigm to disrupt metabolic health profiling and to improve cardiometabolic disease prevention 10.15-10.30 Jane Zhi Chen: The essential role of Th17/Treg cells in inflammation and tumorigenesis 10.30-10.45 Lauri Eklund and Vesa Kiviniemi: Waste clearance in the brain: Pathophysiology in Alzheimer's disease and novel treatment strategies 10.45-11.00 Jian-An Huang and Vahid Farrahi: Digital Raman assay for single-molecule protein sequencing in single live cells 11.00-12.15 Lunch break 12.15-12.30 Peppi Karppinen (Koivunen): Oxygen and 2-oxoglutarate sensing enzymes as novel therapeutic targets in metabolic, neurological and other disease 12.30-12.45 Thomas Kietzmann: Beyond hypoxia-inducible factors: New molecules interacting in hypoxia-signaling and metabolism 12.45-13.00 Lari Lehtiö: Activation mechanisms and inhibition of human mono-ADP-ribosyltransferases 13.00-13.15 Aki Manninen and Gonghong Wei: The ECM control of the prostate cancer genome 13.15-13.30 Eija Pirinen and Karl-Heinz Herzig: Mitochondrial targeting strategies for the treatment of obesity and metabolic diseases 13.30-13.45 Katri Pylkäs: Deciphering inherited breast cancer susceptibility- Integrating diagnostic and novel genomic approaches 13.45-14.15 Coffee 14.15-14.30 Lloyd Ruddock: Identification and molecular characterization of novel pathways for disulfide formation 14.30-14.45 Simo Saarakkala and Miia Jansson: Novel Raman-based reagent-free diagnostics for arthritic disease 14.45-15.00 Terhi Tapiainen and Justus Reunanen: Gut microbiome in obesity from birth to adulthood 15.00-15.15 Aleksei Tiulpin, Jani Tikkanen and Mika Nevalainen: Low-cost screening for future cardiovascular disease incidence with opportunistic CT 15.15-15.45 Closing words and general discussion

If you have any questions, please do not hesitate to contact me.

Kind regards, Teija

Teija Luoto, Management assistant Biocenter Oulu, University of Oulu Tel. +358 2 9448 6103 Street address: Aapistie 5A, 90220 Oulu, Finland Mail address: P.O. Box 5000, FI-90014 University of Oulu, Finland URL: http://www.oulu.fi/biocenter www.oulu.fihttp://www.oulu.fi/yliopisto

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