Dear All, FIN3R Center and Animal Welfare Body of Oulu Laboratory Animal Centre is proud to invite you to the Finnish 3Rs Annual Symposium in Oulu!

We invite everyone (researchers, technicians, caretakers) involved in biomedical research with animal models or novel-approach methods to hear top level presentations by international and national experts on implementing 3R principles in practice. We have prepared two workshops and more than 10 talks by top experts in the field for the three-day event. For more information about the topics and sessions, have a look at the program below!

Finnish 3Rs Annual Symposium University of Oulu, 4-6 November 2024 Kontinkangas campus, Aapistie 5A

WORKSHOPS Early Career Researchers - use the opportunity to brush up your skill and knowledge in power analysis and experimental design in two dedicated workshops (WS). Note: Places for the workshops are limited. Each workshop can accommodate 16-20 participants. Reserve your space in advance!

Monday, 4 November 2024 (room 487B) 13.00-16.00 Power analysis - Petteri Piepponen (University of Helsinki, Finland) Registration for the Power Analysis Workshop is open until 18 October 2024. To register, click herehttps://link.webropolsurveys.com/Participation/Public/a32f0fcc-adda-4a24-a45d-ca4fbe0b2801?displayId=Fin3144399.

Tuesday, 5 November 2024 (room 487B) 9.00-12.00 What's in a hypothesis? What are exploratory and confirmatory studies, and why is it important to be able to tell the difference? - Otto Kalliokoski (University of Copenhagen, Denmark) Registration for the Experimental Design Workshop is open until 18 October 2024. To register, click herehttps://link.webropolsurveys.com/Participation/Public/112d3c65-144f-4c42-89e2-f820fea6ab23?displayId=Fin3144347.

SYMPOSIUM Tuesday, 5 November 2024 (101A, Leena Palotie Hall)

Session 1 Chair: Mikko Airavaara (University of Helsinki, Finland) 13:15-13:30 Welcoming words from the organizers 13:30-14:00 Integrated approaches in toxicology and pharmacology - Dario Greco (University of Tampere, Finland) 14:00-14:30 Anesthetic influence of cerebrospinal fluid dynamics in rodents - Daniel Persson (University of Helsinki, Finland) 14:30-15:15 Coffee and Posters 15:15-15:30 Short oral presentations from abstracts 15:30-16:00 TBA - Thorsten Buch (University of Zurich, Switzerland)

Wednesday, 6 November 2024 (101A, Leena Palotie Hall)

Session 2 Chair: Johanna Englund (University of Helsinki, Finland) 9:00-9:35 Refining models of cardiac fibrosis, from mice to dish - Andreas Romaine (University of Oslo, Norway) 9:35-10:05 Modelling liver complexity with organoids - Anna Dowbaj (Max Planck Institute of Cell Biology and Genetics, Germany) 10:05-10:35 Coffee Break

Session 3 Chair: Vootele Voikar (University of Helsinki, Finland) 10:35-11:10 The 3Hs initiative: Housing, Handling and Habituation methods for rodents - Megan Jackson (University of Bristol, UK) 11:10-11:40 Mastering Mouse Habituation and its Effects on Biomedical Research Outcomes - Julia Swan (University of Eastern Finland, Finland) 11:40- 12:00 Short oral presentations from abstracts 12:00-13:30 Lunch and Posters

Session 4 Chair: Hanna-Marja Voipio (University of Oulu, Finland) 13:30-14:05 TBA 14:05-14:35 Refinement of preclinical research - a focus on experimental design - Gillian Currie (University of Edinburgh, UK) 14:35-15:20 KEYNOTE: How common are fraudulent animal studies and how do they impact us? - Otto Kalliokoski (University of Copenhagen, Denmark) 15:20-15.30 Discussion and closing words

Attending the symposium supports your continuing professional development (CPD). Doctoral researchers can earn additional study credits by presenting their work at the symposium (short oral communication and/or poster). In order to do so, please submit your abstract herehttps://link.webropolsurveys.com/Participation/Public/24bcc537-1eec-483f-a17b-21069afe047b?displayId=Fin3144433 by 30 September!

Registration for the Symposium is open until 1 November 2024. To register, click herehttps://link.webropolsurveys.com/Participation/Public/24bcc537-1eec-483f-a17b-21069afe047b?displayId=Fin3144433. For additional information and questions, please contact Reetta Hinttala at reetta.hinttala@oulu.fimailto:reetta.hinttala@oulu.fi.

Organizing committee: Reetta Hinttala, Mikko Airavaara, Johanna Englund, Anne Heikkinen, Satu Kuure, Sakari Laaksonen, Vootele Voikar and Hanna-Marja Voipio.

Reetta Hinttala, PhD Professor, Molecular Biology in Medicine Research Unit of Clinical Medicine, Faculty of Medicine Coordinator of Transgenic and Tissue Phenotyping Core Facility Biocenter Oulu, INFRAFRONTIER (ESFRI) University of Oulu Finland [cid:image001.png@01DAF554.02C565C0]