Best practice in pre-clinical animal research: Navigating the guidelines and principles

Preclinical studies using animal models are an integral part of biomedical research. However, their value is dependent on their scientific validity and reproducibility, which are, in turn, dependent on rigorous study design and reporting. This symposium aims to update on the guidelines developed and recommended for achieving robust research output.

* When: November 10, 2021; 12:30 –17:00 EET (Finland) * Where: Zoom-meeting * Registration for this meeting is required and open until 14:00 on November 8. * Please use the e-form for registration https://elomake.helsinki.fi/lomakkeet/113272/lomake.html * Link for joining the meeting will be sent to the email of registered participant on November 9. * Organizers: Finnish Reproducibility Networkhttps://www.finnish-rn.org and HiLIFE Comprehensive Model Organisms infrastructure platformhttps://www2.helsinki.fi/en/infrastructures/comprehensive-model-organisms * Further information: vootele.voikar@helsinki.fimailto:vootele.voikar@helsinki.fi

PROGRAM:

12:30-12:55 Hanno Würbel (University of Bern, Switzerland): Making a case for animal research: the 3Vs and 3Rs principles

13:00-13:25 Uli Dirnagl (Charité–UniversitätsmedizinBerlin, Germany): From 3R to 6R: Improve the quality and value of animal experiments in biomedicine

13:30-13:55 Adrian Smith (Norecopa, Norway): The PREPARE guidelines for planning animal research: checklists and resources

14:00-14:15 break

14:15-14:40 Matthew Brooke (NC3Rs, London, UK): Introducing the ARRIVE guidelines 2.0: revised guidelines for reporting animal research

14:45-15:10 Thomas Steckler (Janssen PharmaceuticaNV, Belgium): The EQIPD Quality System

15:15-15:40 Jan Rozman (Czech Centre for Phenogenomics, Czech Republic): Quality principles in INFRAFRONTIER and IMPC -experiences and lessons frominternational large-scale mouse genomics projects

15:45-16:00 break

16:00-17:00 round-table discussion and Q/A session together with Pirjo Laakkonen and Satu Kuure (Laboratory Animal Center, University of Helsinki) and Cilenede Oliveira (UniversidadeFederal de Santa Catarina, Brazil)

_________________________________________ Vootele Võikar, MD, PhD Neuroscience Center / Laboratory Animal Center Helsinki Institute of Life Science (HiLIFE) P.O. Box 29 (Mustialankatu 1G) FI-00014 University of Helsinki Finland

Phone: +358 2941 57658 Mobile: +358 50 416 0466 E-mail: vootele.voikar@helsinki.fimailto:vootele.voikar@helsinki.fi

https://www.helsinki.fi/en/hilife-neuroscience-center https://www.fingmice.fi/mbpf/ e-mail: mbpf@helsinki.fimailto:mbpf@helsinki.fi