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Dr. Laura Kvist Docent in molecular ecology and -evolution Department of Biology University of Oulu Linnanmaa 90014-Oulu Finland e-mail laura.kvist@oulu.fi/ laura.kvist@csc.fi phone: +358-8-5531802 fax: +358-8-5531061

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---------- Forwarded message ---------- Date: Mon, 24 May 2004 23:17:50 -0600 From: Sudhir Kumar release@megasoftware.net To: laura.kvist@oulu.fi Subject: MEGA 3 Beta (test release 5) announcement

Dear Colleague: We are pleased to make available an advanced beta test release of MEGA version 3 (test release 5). You can download MEGA3 (test release 5) from http://www.megasoftware.net/mega3/ .

What's new in MEGA3? 1. Alignment system (a) Manual alignment of DNA and proteins (b) automatic translation/untranslation (codon alignment) (c) Integrated ClustalW. (d) Import sequencer and other format data (e) save alignment sessions 2. Web data mining (a) Integrated web-browser (b) One-click sequence retrieval from GenBank/BLAST 3. Sequence Trace File Editor (a) Intuitive display (b) Manual editing of sequencer trace file (c) Launching BLAST from sequencer trace files (d) trace file printing. 4. Enhanced Tree Explorer (a) Ability to read/write newick format files (b) Add images to groups and taxa. 5. Expanded distance calculations (a) LogDet, JTT, Dayhoff models (b) Relaxation of the homogeneity assumption

A comprehensive list of MEGA's features can be found on the MEGA 3 website at the following address: http://www.megasoftware.net/mega3/features.html

We appreciate your willingness to test drive this version. Please send your comments and bug reports to us at the earliest possible date to allow us to release MEGA3 for use in research and teaching. In the meantime, please do not publish results from this test version, unless you have checked them with the full release of MEGA2 or with other suitable programs.

With best wishes,

Sudhir Kumar, Koichiro Tamura, and Masatoshi Nei MEGA Software Development Team

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