From: bco-bounces(a)lists.oulu.fi [mailto:bco-bounces@lists.oulu.fi] On Behalf
Of anita.tienhaara(a)helsinki.fi
Sent: 16. joulukuuta 2009 9:41
To: FinBioNet
Subject: [Bco] PhD position in male infertility research, University of
Turku
PhD STUDENT POSITION IN MALE INFERTILITY RESEARCH
Candidates are sought for a four year PhD studentship on the regulation of
the sperm tail and cilia development in the laboratory of Jorma Toppari and
Noora Kotaja, Department of Physiology, Institute of Biomedicine, University
of Turku. The position is funded by the Finnish Academy and co-ordinated by
Johanna Vilkki, Biotechnology and Food Research, MTT Agrifood Research
Finland. This project follows up on our previous research characterizing a
mutation in Spef2 gene causing the immotile short tail sperm defect in the
Finnish Yorkshire boars. This project is directed towards understanding the
role of Spef2 in spermatogenesis and cilia development. Cilia defects are
involved in the aetiology of various human diseases and this project will
provide tools to further understanding the biological events underlying
these conditions.
We are looking for highly motivated and ambitious candidates with a
background in genetics, physiology, cell biology or biochemistry. Previous
experience in laboratory methods of cell metabolism, molecular biology,
protein biochemistry and working with laboratory animals would be considered
an advantage. The position is available from the 1st February 2010 or as
soon as possible thereafter.
The closing date for applications is January 15, 2010. To apply, e-mail your
CV and an informal application letter clearly describing your experience on
molecular biology methods to anu.sironen(a)mtt.fi. Also include names and
contact information of three referees.
Recent publications:
Sironen A., Thomsen B., Andersson M., Ahola V., Vilkki J. An intronic
insertion in KPL2 results in aberrant splicing and causes the immotile short
tail sperm defect in the pig. Proc Natl Acad Sci U S A. 2006 Mar
28;103(13):5006-11.
Sironen A., Vilkki J., Bendixen C., Thomsen B. Infertile Finnish Yorkshire
boars carry a full-length LINE-1 retrotransposon within the KPL2 gene. Mol
Genet Genomics 2007 Oct;278(4):385-91.
Sironen A, Thomsen B, Andersson M, Vilkki J, Toppari J, Kotaja N. Possible
role of KPL2 in the organization of sperm tail through intra flagellar
transport in differentiating male germ cells. Biol. Reprod. 2009 Nov 4.
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Anita Tienhaara
Institute of Biotechnology
P.O. Box 56
FIN-00014 University of Helsinki, finland
tel. +358 9 191 59656
fax +358 9 191 59550
anita.tienhaara(a)helsinki.fi