From: bco-bounces@lists.oulu.fi [mailto:bco-bounces@lists.oulu.fi] On Behalf Of anita.tienhaara@helsinki.fi
Sent: 21. tammikuuta 2010 9:55
To: FinBioNet
Subject: [Bco] PhD position in quantitative/statistical genetics, University of Helsinki

PhD position in quantitative/statistical genetics

We seek for a PhD student with background in genetics, bioinformatics or comparable studies to join a large research group working on metapopulation ecology, evolution and functional genomics of the Glanville fritillary butterfly. The PhD project includes construction of a genetic recombination map, designing a genome-wide custom SNP-chip assay, and application of the SNP-chip for association and linkage analyses of flight metabolism.  The Glanville fritillary is a well-known model system in population biology studied since 1991. The project is funded by the European Research Council and the Academy of Finland.

We have recently sequenced the transcriptome of the Glanville fritillary and are currently sequencing the entire genome using Roche 454 Titanium and SOLiD3. The genetic map will be constructed with genome-wide SNP-data from controlled crosses. The custom SNP-chip will be based on sequence-derived information on allele frequencies and functional analyses of SNP variation combined with automated literature search and data from the genetic map.

The SNP-chip platform to be developed in this project will be used in many studies of Glanville fritillary population genetics, evolution and association and linkage analyses of life history and phenotypic traits. This PhD project is primarily focused on genetic variation in flight metabolism, which has high heritability and is under intensive study in the Metapopulation Research Group. In addition to general statistical methods, relevant software packages (Merlin, PLINK, FBAT etc.) will be implemented.    

Deadline for applications is February 19. The application should be sent to Rainer Lehtonen (rainer.lehtonen@helsinki.fi) and it should include a cover letter explaining your background and research interests, CV, and contact information for two referees. Further information about the project and this position may be obtained from Rainer Lehtonen and Ilkka Hanski (ilkka.hanski@helsinki.fi). The web-site of the Metapopulation Research Group is www.helsinki.fi/science/metapop.

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Anita Tienhaara

Institute of Biotechnology

P.O. Box 56

FIN-00014 University of Helsinki, finland

tel. +358 9 191 59656

fax +358 9 191 59550

anita.tienhaara@helsinki.fi