A project suitable as a Pro gradu work to an enthusiastic student!

The project involves studying NF-kB signaling related to oral cancer as well as exosome-mediated transfer of information.

Most of the experiments will be cell culture-based and by using a 3D tumor model developed by our group (Nurmenniemi et al. 2009, Am J Pathol 175: 1281-1291).

Methods that will be used are plasmid-mediated overexpression, siRNA-mediated protein downregulation, different types of migration and invasion experiments, proliferation and viability assays, exosome isolation, immunohistochemistry and confocal microscopy.

There might also be a possibility to continue as a doctoral student later.

The research laboratory is situated at Institute of Dentistry, at the Medical campus, main building, Aapistie 5A.

If you are interested, send e-mail or call.

Emma Pirilä

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Emma Pirilä, PhD, Lab Manager

Institute of Dentistry

Aapistie 5A, 2nd floor

FIN- 90230 University of Oulu

Finland

Phone: +358503426428

e-mail: emma.pirila@oulu.fi

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