From:
bco-bounces@lists.oulu.fi [mailto:bco-bounces@lists.oulu.fi] On Behalf Of anita.tienhaara@helsinki.fi
Sent: 1. marraskuuta 2010 9:30
To: FinBioNet
Subject: [Bco] PhD student position in structure-function studies of
small GTPases in cancer
PhD
student position in structure-function studies of small GTPases in cancer in
the Mechanism and Biosensors of small GTPases Group of Daniel Abankwa at the
Turku Centre for Biotechnology, University of Turku and Åbo Akademi University,
Turku Finland ( www.btk.fi ).
Turku
is a beautiful old city located in South-Western corner of Finland surrounded
by a magnificent archipelago with thousands of small islands ( http://www.saaristo.org/eng/ .
Our
research focuses on the membrane organization and signaling activity of small
GTPases of the Ras-, Rho- and Rab-family. We have recently described a novel
membrane-orientation switch III region for Ras proteins, which profoundly
influences their biology (Abankwa D et al. (2008) Embo J 27(5): 727-735;
Abankwa D et al. (2010) PNAS 107 (3): 1130-1135). We will be using cutting-edge
cellular imaging (Fluorescence Lifetime Imaging Microscopy, FLIM, and
STED-nanoscopy), high-throughput methodological
approaches
(high-content and cytometer chemical- and RNAi-screening) and animal models to
answer exciting questions around this newly discovered mechanism.
The
Centre for Biotechnology offers state-of-the-art research facilities for
bioimaging, proteomics, genomics, crystallography, which support excellence in
research in the greater Turku area. The Cell Imaging Core features very good
equipment for life-cell imaging, high-content and confocal microscopy, as well
as state of the art FACS service and highthroughput
flow
cytometry. In particular, it serves as the Nordic reference site for the Leica
STimulated Emission Depletion (STED)-superresolution microscope.
We
are looking for candidates with exceptional motivation, who recently earned
their masters degree in a discipline related to life sciences or biophysics and
experience and/or interest with protein purification, fluorescence imaging,
flow cytometry and/or animal cancer models. Experience in molecular biology
techniques is indispensable. The stipend 1400 €/month net (not taxable) is
commensurate with typical university salary scales for graduate students.
Please
send preferably as one merged pdf: a short CV that highlights your most
outstanding achievements, as well as the email contacts of 2-3 referees (these
may also be course advisors) and a brief description that highlights your most
outstanding achievements and your specific motivation to join the group
(approx. 1/2 A4 page) to daniel.abankwa-at-btk.fi
with
the subject line "research candidate". The positions commence at the
beginning of 2011. Applications are open from 1. November 2010 until the
positions are filled.
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Anita
Tienhaara
Institute
of Biotechnology
P.O.
Box 56
FIN-00014
University of Helsinki, finland
tel.
+358 9 191 59656
fax
+358 9 191 59550
anita.tienhaara@helsinki.fi