From: Inari Kursula [mailto:inari.kursula@oulu.fi]
Sent: 2. elokuuta 2012 22:19
To: Adrian Goldman
Cc: Rik Wierenga; Anton Zavialov; Veli-Pekka Jaakola; Tiina Salminen; Pirkko Heikinheimo; Juha Rouvinen; Jari Ylänne; Mikko Metsä-Ketelä; Petri Kursula; Sarah Butcher; Tommi Kajander; Tuomo Glumoff; Lari Lehtiö; Tassos Papageorgiou
Subject: Looking for an MSc student

Dear colleagues,

I would be grateful if you could pass this ad on to possibly interested candidates and maybe appropriate mailing lists.

Kind regards,

Inari

MSc student position open in the group of Dr. Inari Kursula, Department of Biochemistry, University of Oulu and Centre for Structural Systems Biology, DESY, Hamburg

We are looking for an enthusiastic and dedicated student with a keen interest in protein chemistry and structural biology to join our young and dynamic group for an MSc (pro gradu) project for about six months, starting as soon as possible. The work can be performed in our laboratories either in Oulu or Hamburg, or shared between both.

My group is working on proteins regulating the actin-based motility of the malaria parasite (Plasmodium). The exact topic of the offered project can be negotiated, somewhat depending on the interests of the candidate. The methods to be used will include some or all of the following: cloning, protein expression and purification using bacterial and baculovirus systems, biochemical and biophysical characterization of protein-protein interactions (SPR, ITC, fluorescence spectroscopy…), fluorescence microscopy, protein crystallization, diffraction data collection, and structure determination. More information on our group and projects can be found at our website: http://www.desy.de/~inari/lab

Informal enquiries by e-mail are most welcome.

Informal enquiries and applications should be addressed to:

Inari Kursula - inari.kursula@helmholtz-hzi.de

Applications will be considered until a suitable candidate has been found.

Recent publications related to the topic:

Ignatev A, Bhargav SP, Vahokoski J, Kursula P & Kursula I (2012) The lasso segment is required for functional dimerization of the Plasmodium formin 1 FH2 domain. PLoS ONE 7: e33586.

Singh BK, Sattler JM, Chatterjee M, Huttu J, Schüler H & Kursula I (2011) Crystal structures explain functional differences in the two actin depolymerization factors of the malaria parasite. J. Biol. Chem., 286: 28256-28264.

Huttu J, Singh BK, Bhargav SP, Sattler JM, Schüler H & Kursula I (2010) Crystallization and preliminary structural characterization of the two actin depolymerization factors of the malaria parasite. Acta Cryst. F, 66: 583-587.

Kursula I, Kursula P, Ganter M, Panjikar S, Matuschewski K & Schüler H (2008) Structural basis for parasite-specific functions of the divergent profilin of Plasmodium falciparum. Structure, 16: 1638-1648.

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Inari Kursula, Asst.Prof.
Helmholtz Centre for Infection Research
and University of Hamburg
CSSB-HZI at DESY
Notkestrasse 85, Bldg. 25b
22607 Hamburg
Germany

and

Department of Biochemistry
University of Oulu
Linnanmaa H4
90570 Oulu
Finland

http://www.desy.de/~inari/
http://www.biochem.oulu.fi/tutkimus/ikursula/
http://cc.oulu.fi/~inkursul/
inari.kursula@helmholtz-hzi.de, inari.kursula@oulu.fi
+49-(0)40-89986151, +358-(0)8-5531184
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