From: bco-bounces@lists.oulu.fi [mailto:bco-bounces@lists.oulu.fi] On Behalf Of anita.tienhaara@helsinki.fi
Sent: 19. huhtikuuta 2010 7:56
To: FinBioNet
Subject: [Bco] PhD position in angiogenesis signaling research in the Molecular/Cancer Biology Program, Biomedicum Helsinki

PhD/Graduate STUDENT POSITION IN ANGIOGENESIS SIGNALING RESEARCH

A Ph/Graduate student position is available in the Molecular/Cancer Biology Program, Biomedicum Helsinki, University of Helsinki in a project lead by Docent Pipsa Saharinen. 

The project is focused on the analysis of Angiopoietin growth factor activated Tie receptor tyrosine kinase signaling, essential for both developmental and pathological angiogenesis and lymphangiogenesis. Research combines e.g. extensive proteomic analyses with imaging of retro- and lentivirus modified endothelial cells and ex vivo tissue culture models with direct connections to in vivo mouse models. The project is funded in part by the Academy of Finland. Position is available immediately, and the start time is negotiable.

Applications should be submitted via e-mail ( Pipsa.Saharinen@Helsinki.fi  and include a letter with a short description of previous research and research interests, CV (including diplomas and transcripts from the university), as well as names and contact information of possible referees (e.g. the supervisor of the Master’s/diploma thesis). For further information, please contact Docent Pipsa Saharinen, tel: +358-40 768 3607, +358-9-1912 5521.

References:

1.         Saharinen et al: Claudin-like protein 24 interacts with the VEGFR-2 and VEGFR-3 pathways and regulates lymphatic vessel development. Genes.Dev. In Press, 2010.

2.         Saharinen et al: How do angiopoietins Tie with vascular endothelial growth factors? Curr. Opin. Hematol. Apr 5. [Epub ahead of print] 2010.               

3.         Saharinen et al: Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts. Nat. Cell. Biol. 10:527-37, 2008.

4.         Saharinen et al: Multiple angiopoietin recombinant proteins activate the Tie1 receptor tyrosine kinase and promote its interaction with Tie2. J. Cell. Biol. 25:239-43, 2005.

5.         Saharinen et al: Lymphatic vasculature: development, molecular regulation and role in tumor metastasis and inflammation. Trends. Immunol. 25: 387-95, 2004.

Complete list of publications can be found at

http://www.ncbi.nlm.nih.gov/pubmed?term=saharinen-p[Author]

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Anita Tienhaara

Institute of Biotechnology

P.O. Box 56

FIN-00014 University of Helsinki, finland

tel. +358 9 191 59656

fax +358 9 191 59550

anita.tienhaara@helsinki.fi