PhD Student, Biochemistry and Molecular Medicine/Medicine, University of Oulu

We are looking for a PhD Student in Biochemistry and Molecular Medicine for a fixed-term two-year position:

https://rekry.saima.fi/certiahome/open_job_view.html?did=5600&lang=en&id=000010988&jc=1

Project

This research project focuses on the interplay between hypoxia signalling, metabolism and fibrosis. The selected student will work under supervision of professors Peppi Karppinen and Terhi Piltonen. The aim of the project is to reveal the causality and relations between these pathways using the sex-hormone driven polycystic ovary syndrome (PCOS) as a disease model. This is a common syndrome in women affecting about 10% the female population. Fibrosis in liver, ovary and adipose tissue is associated with PCOS and may contribute to high comorbidity among affected women. Our main interests are the hypoxia-inducible factor (HIF) and its regulating HIF prolyl 4-hydroxylases. We use mainly molecular and cell biology methods as well as gene-modified mice and preclinical disease models to understand how these pathways interact. This is a project with multidisciplinary approach aiming to answer important clinical questions. We offer a research environment with excellent technological facilities and a motivating and supporting community. More information can be found on our web pages:

https://www.oulu.fi/fbmm/peppi_karppinen

https://www.oulu.fi/mrc/research-groups/piltonen

Requirements

• a degree entitling the applicant to obtain a PhD (MSc or equivalent) preferably in the field of biochemistry, molecular or cell biology, medical sciences or related fields. Degree must have been completed before starting the position and must not be obtained more than 5 years ago.
• Competence to carry out procedures on animals within the EU, proven by the course and practical training certificate.
• Prior experience on animal experiments, preclinical disease models and knowledge on molecular and cellular biology as well as histological and imaging methods are an advantage.
• Ability to pursue independent research, work productively in a team as well as excellent writing and fluency in English are expected.
• The applicant will be enrolled to University of Oulu Graduate School, so the applicant must also fulfill the requirements for admission: https://www.oulu.fi/uniogs/requirements_for_admission .

What we offer

• You will become a part of a highly talented research group, working on strategically and globally significant research area
• The position will be covered 50% as a salary and 50 % as a grant for the two years period. Further information regarding further funding for the PhD project, please contact prof. Karppinen or prof. Piltonen.
• Other benefits: The successful candidate will receive full benefits provided by the University of Oulu to university employees, including free time corresponding to holidays and free occupational health care services.

Application

Applications must be submitted using the electronic application form by April 11, 2021 (23:59 Finnish local time), with the following attachments as three separate pdf files:

1)      Complete CV containing contact information of at least two referees

2)      Motivation letter describing prior knowledge and research interests and career plans (maximum 1 page).

3)      Certificates/Diplomas (please see the full call text for further info)

Other relevant information

The eligible applicants fitting best in the research profile expected for the position may be invited to an on-site or remote interview. All applicants will be notified when the selection process is completed. The earliest start date is 3rd of May 2021. A trial period of six months is applied in the position.

For full recruitment call text and further information, please see: 

https://rekry.saima.fi/certiahome/open_job_view.html?did=5600&lang=en&id=000010988&jc=1

Best regards,

Riikka K. Arffman, PhD,

Post-doctoral fellow, Research manager

Terhi Piltonen Group,

Department of Obstetrics and Gynecology

PEDEGO Research Unit, Medical Research Center

University of Oulu

Mailing address: 

Aapistie 5A/CRC, 3^rd floor

90220 Oulu 

FINLAND

e-mail: riikka.arffman@oulu.fi