From: bco-bounces@lists.oulu.fi [mailto:bco-bounces@lists.oulu.fi] On Behalf Of anita.tienhaara@helsinki.fi Sent: 13. lokakuuta 2010 10:13 To: FinBioNet Subject: [Bco] 9 ESR (PhD) and 4 ER (Post-doctoral) positions in cellular and structural biology

Marie Curie Initial Training Network on Muscle Z-disk Protein Complexes: from atomic structure to physiological function (ITN MUZIC) offers

9 ESR (PhD) and 4 ER (Post-doctoral) positions in cellular and structural biology

All partners except for Stockholm offer ESR positions, Leeds, Stockholm, Vienna and

Hamburg also offer ER positions.

Main Research Field

Cellular and Structural Biology

Job Summary

The Marie Curie Initial Training Network on Muscle Z-disk Protein Complexes: from atomic

structure to physiological function (ITN MUZIC), funded by the European Commission is

filling 9 Doctoral and 4 Postdoctoral positions at 8 Universities/Research Institutions in 6

European countries (from November 2009 on until all positions are filled).

ITN MUZIC aims are

• To bridge the gap between cellular and structural biology by creating a training

program that will incorporate both disciplines in the study of molecular components

and the cellular mechanisms of the muscle Z-disk. Within the network, young

researchers will be trained in a set new, highly versatile research title: “Cellular

Structural Biologist”.

• To advance knowledge in the area of muscle Z-disk protein complexes, interactions

and functions in healthy and diseased cells by understanding the atomic structure of

selected components central to Z-disk integrity, their molecular architecture, the

dynamic changes of the Z-disk interactome and signalling pathways regulating its

development and remodelling.

The ITN MUZIC research programme is organised in four work packages (WP):

• Atomic structure of filamin, telethonin and alpha–actinin in the Z-disk - WP1

• Z-disk Ultrastructure and Molecular Architecture of Its Complexes - WP2

• Dynamic changes of the Z-disk interactome - WP3

• Signalling pathways regulating Z-disk development and remodelling - WP4

Job Description

The partners of ITN MUZIC are dedicated to producing the next generation of research

scholars working in the interdisciplinary field of cellular structural biology. ESR and ER’s

individual projects will be integrated into one comprehensive research and training

network. In order to train Cellular Structural Biologists profile they will be offered an

innovative training in a unique combination of scientific methods that span from biophysical

characterisation of proteins and their complexes, high resolution (X-ray crystallography) and

low resolution structural biology methods (SAXS, EM, cryo‐EM tomography, atomic force

microscopy) to a variety of cell biology oriented techniques, ranging from FRET and live-cell

imaging, cellular and animal models to animal physiology.

The network is strongly based on the exchange and transfers of knowledge between

participating institutions and will provide its fellows with network-wide training activities

(workshops, summer schools, scientific symposium) and training-in-collaborations (working

visits and secondments).

ITN MUZIC partners and their fields of research:

1. Kristina Djinovic Carugo (Coordinator, Univ. Vienna, Austria) – Structural Biology of ZDisk

with focus on the a‐actinin interactome (WP1, WP2); to apply send application to

muzic@univie.ac.at , for more information contact kristina.djinovic@univie.ac.at

2. Dieter Fürst (Univ. Bonn, Germany) – Cell Biology of Z-Disk with focus on protein

localization, dynamics and interactions in living cells (WP3, WP4); to apply send

application to zellbiologie@uni‐bonn.de , for more information contact dfuerst@unibonn.

de

3. Stefano Schiaffino and Gerolamo Lanfranchi (Univ. Padova, Italy) - Cell Biology of ZDisk

with focus on signalling pathways involved in mechanical stimuli and on functional

genomic analysis of muscle cell silencing (WP4); to apply send application to

stefano.schiaffino@unipd.it or gerolamo.lanfranchi@unipd.it , for more information

contact stefano.schiaffino@unipd.it or gerolamo.lanfranchi@unipd.it

4. Matthias Wilmanns (EMBL‐Hamburg, Germany) - Structural Biology of Z-Disk with

focus on the titin interactome(WP1, WP2); to apply send application wilmanns@emblhamburg.de , for more information contact wilmanns@embl‐hamburg.de

5. Jari Ylänne (Univ. Jyväskylä, Finland) – Structural and Cell Biology of Z-Disk with focus

on intra‐subunit interactions in filamin (WP1, WP2, WP3); to apply send application

contact jylanne@bytl.jyu.fi , for more information contact jylanne@bytl.jyu.fi

6. John Trinick (Univ. Leeds, UK) - Structural Biology of Z-Disk with focus on the Z-disk

ultrastructure (WP2); to apply send application to j.trinick@leeds.ac.uk , for more

information contact j.trinick@leeds.ac.uk

7. Mathias Gautel (King’s College London, UK) – Cell Biology of Z-Disk with focus on

regulation of Z-disk protein interactions by phosphorylation (WP2, WP3, WP4); to apply

send application to mathias.gautel@kcl.ac.uk , for more information contact

mathias.gautel@kcl.ac.uk

8. Matthias Rief (Technical University Muenchen, Germany) – Structural Biology of ZDisk

with focus on biomechanical properties of filamin (WP1, WP2); to apply send

application to mrief@ph.tum.de , for more information contact mrief@ph.tum.de

9. Evitra AB (Stockholm, Sweden) – Protein production (WP1, WP2); to apply send

application to Marina.Sabet@ki.se , for more information contact

Marina.Sabet@ki.se or Par.Nordlund@ki.se

Early Stage Researchers

Must be in the first 4 years (full-time equivalent) of research career since gaining a

university diploma giving access to doctoral studies.

• The length of individual appointment will be limited to between 3 and 36 months.

• The basic gross living allowance for the Early Stage Researcher Fellowships is up to about

33.800 €/year mobility allowance + travel allowance + career exploratory allowance

Experienced Researchers

• Must either be in possession of a doctoral degree or have at least 4 years of full-time

equivalent research experience;

• The research experience may not exceed 5 years at the time of appointment.

• The length of individual appointment will be limited from 3 to 24 months.

• The basic gross living allowance for the Experienced Researcher Fellowships is up to about

52.000 €/year mobility allowance + travel allowance + career exploratory allowance

All candidates must NOT be nationals of the country where they seek employment, or

have legally resided or have had their main activity in that country for more than 12

months in the 3 years immediately prior to the starting date.

For more information on the recruitment and allowances please see the Annex III to the

Grant Agreement from pages 8 – 11: ftp://ftp.cordis.europa.eu/pub/fp7/docs/fp7‐mgaannex3intramulti_en.pdf

For further information on these vacancies please see

http://www.mfpl.ac.at/index.php?cid=887

and contact individual Partners.

Application deadline: till positions are filled.

The completed application form, official diploma document and the letters of recommendation have to be sent to individual Partners.

Application form download: http://www.mfpl.ac.at/getdownload.php?id=168

Please indicate which institution(s) you would like to be considered for in the application.

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Anita Tienhaara

Institute of Biotechnology

P.O. Box 56

FIN-00014 University of Helsinki, finland

tel. +358 9 191 59656

fax +358 9 191 59550

anita.tienhaara@helsinki.fi