-----Original Message----- From: bco-bounces@lists.oulu.fi [mailto:bco-bounces@lists.oulu.fi] On Behalf Of Anita Tienhaara Sent: 16. syyskuuta 2011 10:09 To: finbionet Subject: [Bco] Are you interested in developmental biology? PhD student position at Institute of Biotechnology, UH

Are you interested in developmental biology? Would you like to understand why and how approximately 1% of the newborns exhibit renal malformations?

I�m looking for a PhD student for the project studying renal differentiation in different mouse models with genetic defects in receptor tyrosine kinase signaling. The aim of the work is to figure out which mechanisms are pivotal for normal development of kidney, and therefore potentially contribute to foetal diagnostics as well treatment of these diseases in future. The study is supervised by me, and carried out at the Institute of Biotechnology in the group lead by Professor Mart Saarma. Applicants are expected to have experience in molecular biology and lab work, but most importantly show enthusiasm towards learning new things and technologies. Previous skills in developmental biology are acknowledged but not required.

Looking forward your contact for further information!

Satu Kuure, PhD Post Doctoral Fellow satu.kuure@helsinki.fi Institute of Biotechnology tel. +358 9 191 59395 cell +359 40 770 6242

Selected publications:

Kuure S, Cebrian C, Machingo Q, Lu BC, Chi X, Hyink D, D'Agati V, Gurniak C, Witke W, Costantini F. 2010. Actin depolymerizing factors cofilin1 and destrin are required for ureteric bud branching morphogenesis. PLoS Genet. 6:e1001176

Kuure, S., Chi,. X., Lu, B., Costantini, F. 2010. The transcription factors Etv4 and Etv5 mediate formation of the ureteric bud tip domain during kidney development. Development. 137:1975-1979.

Lu, B., Cebrian, C., Chi, X., Kuure, S., Kuo, R., Bates, C.M., Arber, S., Hassell, J., MacNeil, L., Schmidt-Ott, K., Barasch, J., D�Agati, V., Costantini, F. 2009. The ETS transcription factors Pea3 and Erm are required downstream of GDNF and Ret for branching morphogenesis during kidney development. Nat Genet. 41:1295-302.

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