-----Original Message----- From: bklist-bounces@lists.oulu.fi [mailto:bklist-bounces@lists.oulu.fi] On Behalf Of Pia Askonen Sent: 30. elokuuta 2011 9:52 To: Bklist@lists.oulu.fi Subject: [Bklist] FW: [Bco] PhD student position in macromolecular crystallography unit, University of Helsinki

-----Original Message----- From: bco-bounces@lists.oulu.fi [mailto:bco-bounces@lists.oulu.fi] On Behalf Of Anita Tienhaara Sent: 30. elokuuta 2011 8:30 To: finbionet Subject: [Bco] PhD student position in macromolecular crystallography unit, University of Helsinki

Institute of Biotechnology, University of Helsinki, macromolecular crystallography unit invites applications for a

DOCTORAL STUDENT POSITION

in neuronal leucine rich repeat protein binding interactions and structural studies (for fixed term of maximum 3 years, starting January 1st 2012).

Doctoral student position is available in structural and biochemical studies of neuronal synaptic leucine rich repeat proteins (LRR), such as LRRTMs and their ligands, neurexins. The goal is to obtain crystal structures of LRR proteins with their ligands and design of inhibitors to study function of these proteins with collaborators, and secondly to study folding of these proteins in vivo/in vitro. Biochemical characterization of binding and cloning and expression and protein engineering of different constructs will form the first part of the work. Several constructs are already available for expression and preliminary result exist.

An appointee to the position of doctoral student shall hold a second-cycle degree and have an approved research proposal. Other requirements shall include the ability and motivation, as demonstrated in previous degree studies or otherwise, to pursue postgraduate studies and a doctoral degree according to the study plan and research proposal. Experience in either molecular biology, cell culture or protein purification and expression is required.

The salary will be commensurate with qualifications based on the university salary system.

Send your application not later than 31 October 2011. at 3.45 PM (CET). Application should be written in English, include a cover letter, CV and contact information of at least one referee. Contact for further inquiries and send applications to:

Tommi Kajander, Ph.D, Junior PI, Academy Research Fellow Institute of Biotechnology Research Program in Structural Biology and Biophysics Biocenter 3, 4th floor PL 65, 00014 University of Helsinki

email: tommi.kajander(at)helsinki.fi, +358 9 191 58903

For further information on site of research please visit our website at www.biocenter.helsinki.fi/bi/

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