----- Edelleenvälitetty viesti lähettäjältä anita.tienhaara@helsinki.fi ----- Päiväys: Wed, 29 Jun 2011 08:18:36 +0300 Lähettäjä: Anita Tienhaara anita.tienhaara@helsinki.fi Vastausosoite: Anita Tienhaara anita.tienhaara@helsinki.fi Otsikko: [Bco] PhD position at the Department of Biochemistry, University of Oulu Vastaanottaja: finbionet finbionet@helisci.fi

A PhD student position is available in the group of Dr. Petri Kursula, to use neutron scattering methods to study proteins specifically expressed in the vertebrate myelin sheath. These proteins have functions e.g. in the interactions between the myelin sheath and the axon, and in the compaction of the multilayered myelin membrane.

The project will involve large-scale recombinant expression of myelin proteins and studying their structure and function using mainly neutron scattering. The student will focus on the structure and dynamics of myelin proteins and their complexes, as well as their interactions with membranes. Complementary experiments will be carried out using X-rays and other biochemical/biophysical methods.

The ideal candidate will: - have an MSc degree in biochemistry, physics, or a related field - have experience in recombinant protein expression and purification and/or in X-ray and neutron scattering methods - be genuinely interested in using neutrons to study biological macromolecules - be fluent in English

The selected candidate will be affiliated with the Department of Biochemistry, University of Oulu, Finland, but a large part of the work is expected to be carried out at the Centre for Structural Systems Biology (CSSB-HZI), on-site the DESY synchrotron campus, Hamburg, Germany. The work will also involve carrying out measurements at international neutron infrastructures, and will be carried out in collaboration with staff at such facilities, including the ILL (Grenoble). The position will be funded by the European Spallation Source (ESS).

More information about our group can be found at www.biochem.oulu.fi/kursula, and informal queries by email are also welcome.

To apply, please send your cv, including list of publications, plus the names and email addresses of 2-3 referees by email to petri.kursula@oulu.fi. The application deadline is July 31st, 2011.

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