PhD Scholarship: Structural and functional studies of eukaryotic membrane proteins involved in cholesterol and sugar transport.

A PhD position is available in membrane protein biochemistry and X-ray crystallography in the newly established research group of Dr. Bjorn P Pedersen at the Department of Molecular Biology and Genetics, Aarhus University, Denmark.

Our group studies the structure-function relationship of membrane proteins involved in metabolite uptake in the human body, primarily cholesterol and sugar uptake, as well as their regulation from a structural perspective. The PhD project will involve expression, purification and structural/functional characterization of membrane proteins involved in metabolite transport. Methods learned and used will be X-ray crystallography and cryo-electron microscopy as well as various biochemical methods to elucidate function.

The project is fully funded by the Danish Council for Independent Research for 3 years (3-year PhD), and will be based in the laboratory of Dr. Bjorn P. Pedersen. It would ideally suit an outstanding biochemistry graduate with a strong interest in structural biology. The candidate should have molecular biology, protein production and purification experience. Experience with membrane proteins or protein structure determination will be an advantage. Full training will be provided in all necessary areas of protein biochemistry and structural biology. Good English language skills are essential. Salary will be according to the collective agreement between the Danish Confederation of Professional Associations and the Danish State. The position will be filled as soon as a suitable candidate is identified.

Applicant should send a CV, cover letter and names of 2 referees to Dr. Bjorn P Pedersen (bpp@mbg.au.dk).