-----Original Message----- From: bco-bounces@lists.oulu.fi [mailto:bco-bounces@lists.oulu.fi] On Behalf Of Anita Tienhaara Sent: 29. maaliskuuta 2011 11:04 To: finbionet@helisci.fi Subject: [Bco] Postdoc or PhD position in the GTPases Group of Daniel Abankwa, Turku

1 Postdoc or PhD position in time resolved fluorescence imaging of molecular players in cancer for 1-3 years

in the Mechanism and Biosensors of small GTPases Group of Daniel Abankwa at the Turku Centre for Biotechnology, University of Turku and �bo Akademi University, Turku Finland (www.btk.fi). Turku is a beautiful old city located in south-western corner of Finland surrounded by a magnificent archipelago with thousands of small islands (http://www.saaristo.org/eng/).

Our research focuses on the membrane organization and signaling activity of small GTPases of the Ras-, Rho- and Rab-family. We have recently described a novel switch III region for Ras proteins, which is associated with formerly unappreciated conformers of membrane bound Ras. This mechanism profoundly influences Ras biology (Abankwa D et al. (2008) Embo J 27(5): 727-735; Abankwa D et al. (2010) PNAS 107(3): 1130-1135). We will be using cutting-edge cellular imaging (FCS, FLIM, and STED-nanoscopy), high-throughput approaches (high-content and cytometer chemical- and RNAi-screening) and animal models to answer exciting questions around this newly discovered mechanism.

The Centre for Biotechnology offers state-of-the-art research facilities for bioimaging, proteomics, genomics and crystallography, which support excellence in research in the greater Turku area. The Cell Imaging Core features state-of-the-art equipment for life-cell imaging, high-content and confocal microscopy, as well FACS services and high-throughput flow cytometry. In particular, it serves as the Nordic reference site for the Leica STimulated Emission Depletion (STED)-superresolution microscope.

We are looking for candidates with exceptional motivation and proven track record of successful scientific/ academic work, who have a (bio-)physics background and earned their PhD/ Masters degree in a discipline related to life sciences with in experience/ interest in FLIM and/or FCS or related methods. Experience and/or interest in molecular biology techniques and/or in protein purification is an advantage.

The salary is in accordance with the University salary system (for teaching and research personnel) level 5-6 or 1-2 (grad. student), where the work specific salary component is between 2714- 3183 �/month or 1707- 1847 �/month (grad. student). In addition, there is a share increase based on the personal performance, which is at most 46% of the base salary.

Please send preferably as one merged pdf: a short CV, as well as the email contacts of 2-3 referees and a brief description that highlights your most outstanding achievements and your specific motivation to join the group (approx. 1/2 A4 page) to daniel.abankwa@btk.fi with the subject line �PostDoc candidate�. The position commences from June 2011. Applications are open now until the positions are filled.

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