Dear all,
The Biocenter Oulu Discovery of the Year 2025 Event was held on December 15.
BCO Discovery of the year 2025: Orexin effect on physiological pulsations of the human brain.https://pubmed.ncbi.nlm.nih.gov/40748959/ Proc Natl Acad Sci U S A. 2025 Aug 5;122(31):e2501578122 Järvelä M, Kananen J, Helakari H, Korhonen V, Huotari N, Väyrynen T, Hautamäki K, Raitamaa L, Tuunanen J, Kallio M, Piispala J, Ansakorpi H, Kiviniemi V. Presentation by Matti Järvelä
The Best Poster 2025 voted by the audience: MauE, a new disulfide bond formation pathway Cassandra P. Gonzalez, Antti Moilanen, Kati Korhonen, Thu Nguyen Pham Anh, Joonatan Hiltunen and Lloyd W. Ruddock Presented by Cassandra Gonzalez
Congratulations! ------------------------------------------------------------------------------------------------------------------ The other publications presented in the event were the following (not in the ranked order):
Ccer1https://pubmed.ncbi.nlm.nih.gov/39868420/ is a spermatid-specific gene required for spermatogenesis and male fertility.https://pubmed.ncbi.nlm.nih.gov/39868420/ Int J Dev Biol. 2024;68(4):251-262 Sammer B, Schmid P, Miyata H, Kazi S, Honkimaa AL, Petrov P, Kapiainen E, Miinalainen I, Izzi V, Ikawa M, Prunskaite-Hyyryläinen R. Presentation by Bianca Sammer
Pulmonary Aspergillosis and Low HIES Score in a Family with STAT3 N-Terminal Domain Mutation.https://pubmed.ncbi.nlm.nih.gov/39928202/ J Clin Immunol 2025 Feb 10;45(1):73. Lima de Souza S, Asano T, Glumoff V, Keskitalo S, Pikkarainen K, Martelius T, Kaustio M, Saarela J, Kuismin O, Lappi-Blanco E, Jartti A, Yannopoulos F, Tiitto L, Seppänen MRJ, Boisson B, Casanova JL, Varjosalo M, Hautala T, Chen Z. Presentation by Keela Pikkarainen
The glycosaminoglycan chains of https://pubmed.ncbi.nlm.nih.gov/40340918/ perlecanhttps://pubmed.ncbi.nlm.nih.gov/40340918/ regulate the perivascular fluid transport.https://pubmed.ncbi.nlm.nih.gov/40340918/ Fluids Barriers CNS. 2025 May 8;22(1):48 Singh A, Kaakinen M, Elamaa H, Kiviniemi V, Eklund L. Presentation by Mika Kaakinen
Targeting HIF-P4H-2 in APP/PS1 Alzheimer's mouse model improves glucose metabolism, reduces dystrophic neuritis, and maintains exploratory activity.https://pubmed.ncbi.nlm.nih.gov/40609789/ J Biol Chem. 2025 Aug;301(8):110432 Kurkela M, Dvořáková L, Koivisto H, Uusitalo M, Kursula P, Kettunen M, Gröhn O, Tanila H, Koivunen P. Presentation by Margareta Kurkela
Discovery of Inhibitors for Bacterial https://pubmed.ncbi.nlm.nih.gov/40509881/ Arrhttps://pubmed.ncbi.nlm.nih.gov/40509881/ Enzymes ADP-https://pubmed.ncbi.nlm.nih.gov/40509881/Ribosylatinghttps://pubmed.ncbi.nlm.nih.gov/40509881/ and Inactivating Rifamycin Antibiotics.https://pubmed.ncbi.nlm.nih.gov/40509881/ ACS Chem. Biol. 2025, 20, 1584−1593 Alaviuhkola J, Abdulmajeed S, Sowa ST, Pääkkönen J, Lehtiö L. Presentation by Juho Alaviuhkola
Congratulations! Wishing you all a relaxing holiday season!
Best wishes, Mirja ------------------------------------------------------------------------------------ Mirja Peltola, PhD, BSc (Tech.) Oulun yliopisto | University of Oulu Biocenter Oulu Cofund MSCA Data4Healthcarehttps://www.oulu.fi/en/university/faculties-and-units/biocenter-oulu/data4healthcare Programme Programme Manager, Coordinator Tel. +358 294 48 5447 PO Box 5000, FI-90014 OULUN YLIOPISTO (Aapistie 5A, Room 476B) www.oulu.fihttp://www.oulu.fi/yliopisto [cid:image001.png@01DC6DE1.FCC413D0]
