The Biocenter Oulu Discovery of the Year 2021 event was held on December 15, 2021 remotely. We had high hopes for a real event with posters … but maybe next year.
Discovery of the year 2021:
Presented by Joona Tapio Systematic evaluation of the association between hemoglobin levels and metabolic profile implicates beneficial effects of hypoxia.https://pubmed.ncbi.nlm.nih.gov/34261659/ Auvinen J, Tapio J, Karhunen V, Kettunen J, Serpi R, Dimova EY, Gill D, Soininen P, Tammelin T, Mykkänen J, Puukka K, Kähönen M, Raitoharju E, Lehtimäki T, Ala-Korpela M, Raitakari OT, Keinänen-Kiukaanniemi S, Järvelin MR, Koivunen P. Sci Adv. 2021 Jul 14;7(29):eabi4822. doi: 10.1126/sciadv.abi4822. Print 2021 Jul.PMID: 34261659
The other publications presented in the event were the following (not in the ranked order):
Cardiovascular brain impulses in Alzheimer's disease.https://pubmed.ncbi.nlm.nih.gov/33787890/ Rajna Z, Mattila H, Huotari N, Tuovinen T, Krüger J, Holst SC, Korhonen V, Remes AM, Seppänen T, Hennig J, Nedergaard M, Kiviniemi V. Brain. 2021 Aug 17;144(7):2214-2226. doi: 10.1093/brain/awab144.PMID: 33787890
Activation of pregnane X receptor induces atherogenic lipids and PCSK9 by a SREBP2-mediated mechanism.https://pubmed.ncbi.nlm.nih.gov/33687065/ Karpale M, Käräjämäki AJ, Kummu O, Gylling H, Hyötyläinen T, Orešič M, Tolonen A, Hautajärvi H, Savolainen MJ, Ala-Korpela M, Hukkanen J, Hakkola J. Br J Pharmacol. 2021 Jun;178(12):2461-2481. doi: 10.1111/bph.15433. Epub 2021 May 14.PMID: 33687065
Activation of PARP2/ARTD2 by DNA damage induces conformational changes relieving enzyme autoinhibition.https://pubmed.ncbi.nlm.nih.gov/34108479/ Obaji E, Maksimainen MM, Galera-Prat A, Lehtiö L. Nat Commun. 2021 Jun 9;12(1):3479. doi: 10.1038/s41467-021-23800-x.PMID: 34108479
Exome sequencing identifies a recurrent variant in SERPINA3 associating with hereditary susceptibility to breast cancer.https://pubmed.ncbi.nlm.nih.gov/33279852/ Koivuluoma S, Tervasmäki A, Kauppila S, Winqvist R, Kumpula T, Kuismin O, Moilanen J, Pylkäs K. Eur J Cancer. 2021 Jan;143:46-51.
Uniting biobank resources reveals novel genetic pathways modulating susceptibility for atopic dermatitis.https://pubmed.ncbi.nlm.nih.gov/34454985/ Sliz E, Huilaja L, Pasanen A, Laisk T, Reimann E, Mägi R; FinnGen; Estonian Biobank Research Team, Hannula-Jouppi K, Peltonen S, Salmi T, Koulu L, Tasanen K, Kettunen J. J Allergy Clin Immunol. 2021 Aug 27;S0091-6749(21)01303-8. doi: 10.1016/j.jaci.2021.07.043
Congratulations to all research teams!
Wishing you All relaxing and safe Christmas and Happy New Year 2022 !
Teija Luoto, Management assistant Biocenter Oulu, University of Oulu Tel. +358 2 9448 6103 Street address: Aapistie 5A, 90220 Oulu, Finland Mail address: P.O. Box 5000, FI-90014 University of Oulu, Finland URL: http://www.oulu.fi/biocenter www.oulu.fihttp://www.oulu.fi/yliopisto
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