A project suitable as a Pro gradu work to an enthusiastic student!
The project involves studying NF-kB signaling related to oral cancer as well as exosome-mediated transfer of information. Most of the experiments will be cell culture-based and by using a 3D tumor model developed by our group (Nurmenniemi et al. 2009, Am J Pathol 175: 1281-1291). Methods that will be used are plasmid-mediated overexpression, siRNA-mediated protein downregulation, different types of migration and invasion experiments, proliferation and viability assays, exosome isolation, immunohistochemistry and confocal microscopy.
There might also be a possibility to continue as a doctoral student later.
The research laboratory is situated at Institute of Dentistry, at the Medical campus, main building, Aapistie 5A.
If you are interested, send e-mail or call.
Emma Pirilä
************************ Emma Pirilä, PhD, Lab Manager Institute of Dentistry Aapistie 5A, 2nd floor FIN- 90230 University of Oulu Finland Phone: +358503426428 e-mail: emma.pirila@oulu.fimailto:emma.pirila@oulu.fi ************************