MSc student position open in the group of Dr. Inari Kursula, Department of Biochemistry, University of Oulu and Centre for Structural Systems Biology, DESY, Hamburg
We are looking for an enthusiastic and dedicated student with a keen interest in protein chemistry and structural biology to join our young and dynamic group for an MSc (pro gradu) project for about six months, starting as soon as possible. The work can be performed in our laboratories either in Oulu or Hamburg, or shared between both.
My group is working on proteins regulating the actin-based motility of the malaria parasite (Plasmodium). The exact topic of the offered project can be negotiated, somewhat depending on the interests of the candidate. The methods to be used will include some or all of the following: cloning, protein expression and purification using bacterial and baculovirus systems, biochemical and biophysical characterization of protein-protein interactions (SPR, ITC, fluorescence spectroscopy...), fluorescence microscopy, protein crystallization, diffraction data collection, and structure determination. More information on our group and projects can be found at our website: http://www.desy.de/~inari/lab Informal enquiries by e-mail are most welcome.
Informal enquiries and applications should be addressed to: Inari Kursula - inari.kursula@helmholtz-hzi.de
Applications will be considered until a suitable candidate has been found.
Recent publications related to the topic:
Ignatev A, Bhargav SP, Vahokoski J, Kursula P & Kursula I (2012) The lasso segment is required for functional dimerization of the Plasmodium formin 1 FH2 domain. PLoS ONE 7: e33586.
Singh BK, Sattler JM, Chatterjee M, Huttu J, Schüler H & Kursula I (2011) Crystal structures explain functional differences in the two actin depolymerization factors of the malaria parasite. J. Biol. Chem., 286: 28256-28264.
Huttu J, Singh BK, Bhargav SP, Sattler JM, Schüler H & Kursula I (2010) Crystallization and preliminary structural characterization of the two actin depolymerization factors of the malaria parasite. Acta Cryst. F, 66: 583-587.
Kursula I, Kursula P, Ganter M, Panjikar S, Matuschewski K & Schüler H (2008) Structural basis for parasite-specific functions of the divergent profilin of Plasmodium falciparum. Structure, 16: 1638-1648.
------------------------------------------------------------------------- Inari Kursula, Asst.Prof. Helmholtz Centre for Infection Research and University of Hamburg CSSB-HZI at DESY Notkestrasse 85, Bldg. 25b 22607 Hamburg Germany
and
Department of Biochemistry University of Oulu Linnanmaa H4 90570 Oulu Finland
http://www.desy.de/~inari/lab http://www.biochem.oulu.fi/tutkimus/ikursula/ http://cc.oulu.fi/~inkursul/ inari.kursula@helmholtz-hzi.de, inari.kursula@oulu.fi +49-(0)40-89986151, +358-(0)8-5531188
Dear All,
I would be grateful if you could pass this ad for possibly interested candidates and maybe appropriate mailing lists.
Kind regards, Inari
MSc student position open in the group of Dr. Inari Kursula, Department of Biochemistry, University of Oulu and Centre for Structural Systems Biology, DESY, Hamburg
We are looking for an enthusiastic and dedicated student with a keen interest in protein chemistry and structural biology to join our young and dynamic group for an MSc (pro gradu) project for about six months, starting as soon as possible. The work can be performed in our laboratories either in Oulu or Hamburg, or shared between both.
My group is working on proteins regulating the actin-based motility of the malaria parasite (Plasmodium). The exact topic of the offered project can be negotiated, somewhat depending on the interests of the candidate. The methods to be used will include some or all of the following: cloning, protein expression and purification using bacterial and baculovirus systems, biochemical and biophysical characterization of protein-protein interactions (SPR, ITC, fluorescence spectroscopy…), fluorescence microscopy, protein crystallization, diffraction data collection, and structure determination. More information on our group and projects can be found at our website: http://www.desy.de/~inari/lab Informal enquiries by e-mail are most welcome.
Informal enquiries and applications should be addressed to: Inari Kursula - inari.kursula@helmholtz-hzi.de
Applications will be considered until a suitable candidate has been found.
Recent publications related to the topic:
Ignatev A, Bhargav SP, Vahokoski J, Kursula P & Kursula I (2012) The lasso segment is required for functional dimerization of the Plasmodium formin 1 FH2 domain. PLoS ONE 7: e33586.
Singh BK, Sattler JM, Chatterjee M, Huttu J, Schüler H & Kursula I (2011) Crystal structures explain functional differences in the two actin depolymerization factors of the malaria parasite. J. Biol. Chem., 286: 28256-28264.
Huttu J, Singh BK, Bhargav SP, Sattler JM, Schüler H & Kursula I (2010) Crystallization and preliminary structural characterization of the two actin depolymerization factors of the malaria parasite. Acta Cryst. F, 66: 583-587.
Kursula I, Kursula P, Ganter M, Panjikar S, Matuschewski K & Schüler H (2008) Structural basis for parasite-specific functions of the divergent profilin of Plasmodium falciparum. Structure, 16: 1638-1648.
------------------------------------------------------------------------- Inari Kursula, Asst.Prof. Helmholtz Centre for Infection Research and University of Hamburg CSSB-HZI at DESY Notkestrasse 85, Bldg. 25b 22607 Hamburg Germany
and
Department of Biochemistry University of Oulu Linnanmaa H4 90570 Oulu Finland
http://www.desy.de/~inari/lab http://www.biochem.oulu.fi/tutkimus/ikursula/ http://cc.oulu.fi/~inkursul/ inari.kursula@helmholtz-hzi.de, inari.kursula@oulu.fi +49-(0)40-89986151, +358-(0)8-5531188 -------------------------------------------------------------------------