Crc September 2024

crc@lists.oulu.fi

18 participants
57 discussions

Veripalvelun tutkimusapurahat 2024 nyt haettavissa (haku päättyy 12.5.2024) / The application period for Blood Service research grants for 2024 is now open (deadline 12.5.2024)
by Mirko Maksimainen 08 Apr '25

08 Apr '25

Hyvät tutkijat / Dear researchers, Veripalvelun tutkimusrahaston vuoden 2024 apurahojen haku tutkijoille on avautunut. Apurahojen tavoitteena on tukea tutkimusta, joka liittyy Veripalvelun nykyisiin ja tuleviin valmisteisiin ja palveluihin. Soveltuvia tieteenaloja ovat esimerkiksi biolääketiede ja kliininen lääketiede, tekniikan ala, sekä hoito-, yhteiskunta- ja terveystaloustieteet. Hakuaika on 5.4.– 12.5.2024. Apuraha voi olla suurimmillaan jopa 150 000 euroa. Lisää tietoa saatavissa täällä: https://www.sttinfo.fi/tiedote/70133993/veripalvelun-tutkimusapurahat-2024-… *********************************************** The call for applications for the 2024 Blood Services Research Fund grants for researchers is now open. The grants aim to support research related to current and future Blood Service products and services. Suitable disciplines include biomedical and clinical medicine, engineering, and nursing, social and health sciences. The application period is from 5 April to 12 May 2024, with a maximum grant of up to €150 000. More information available here: https://www.veripalvelu.fi/en/the-application-period-for-blood-service-rese… Terveisin / Best wishes, Mirko ______________________________________________ Mirko Maksimainen, FT | PhD. Tutkimusrahoitusasiantuntija | Research Funding Specialist Tutkimus- ja Projektipalvelut | Research and Project Services Oulun yliopisto | University of Oulu Tel. +358 29 448 5414 Mobile +358 50 479 2506

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ASA-aineet / ASA carcinogenic substances
by Antti Haapalainen 25 Mar '25

25 Mar '25

Hei, CRC:llä on käytetty aiemmin seuraavia ASA-aineita: kloroformi, akryyliamidi, trypan blue, formaldehydi, nikkelikloridi ja kobolttikloridi. Ne, jotka ovat käyttäneet näitä ASA-aineita vuonna 2022, ilmoittakaa minulle aine, määrä (ml) per vuosi ja liuoksen pitoisuus (%). Ilmoittakaa, jos olette käyttäneet jotain muuta ASA-ainetta (liite "syopasairauden-vaaraa-aiheuttavat-tekijat"). Työterveyslaitoksen ohjeen mukaan jatkossa on ilmoitettava sekä syöpäsairauden vaaraa aiheuttavat tekijät ja perimää vaurioittavat aineet. Nämä molemmat on listattuna liitteen taulukossa 1. Eli ilmoittakaa minulle myös vuonna 2022 käyttämänne perimää vaurioittavat aineet. Ja samaten perimää vaurioittavien aineiden kohdalla aine, määrä (ml) per vuosi ja liuoksen pitoisuus (%). Ilmoittakaa nämä minulle viimeistään 27.3. Hi, The following ASA (carcinogenic) chemicals have been used in CRC previously: chloroform, acrylamide, trypan blue, formaldehyde, nickel chloride and cobolt chloride. Those who have used these ASA chemicals in 2022, please tell me the substance, the amount (ml) per year and the concentration of the solution (%). Also inform me if you have used any other ASA chemicals (Appendix "syopasairauden-vaaraa-aiheuttavat-tekijat"). According to the instructions of the National Institute of Occupational Health, both the factors causing the risk of cancer and the mutagens must be reported from now on. Both of these are listed in Table 1 in the Annex. So, please also let me know the mutagens you used in 2022. And likewise, for mutagenic substances, the substance (ml) per year and the concentration (%) of the solution. Let me know these by 27.3. Terv. Antti Haapalainen

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NanoDrop
by Antti Haapalainen 05 Feb '25

05 Feb '25

Hei, CRC:n NanoDrop (374B) ei toimi kunnolla. Ilmoittelen kun NanoDrop on saatu kuntoon. Voitte käyttää 4. kerroksen NanoDropia (438A). CRC's NanoDrop (374B) does not work properly. I'll let you know when NanoDrop is fixed. You can use the 4th floor NanoDrop (438A). Terv. Antti

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Huoneen 362B Bio-Rad PCR laite / Bio-Rad PCR device in 362B
by Antti Haapalainen 23 Jan '25

23 Jan '25

Hei, Huoneessa 362B olevan PCR laitteen (Bio-Rad C1000) kansi on rikki. Ilmoitan heti kun laite on korjattu. Hi, The cover of the PCR device (Bio-Rad C1000) in room 362B is broken. I will let you know as soon as the device is repaired. Terv. Antti

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Vetokaappien ja laminaarien siivous
by Antti Haapalainen 08 Jan '25

08 Jan '25

Hei, CRC:n laminaarit ja vetokaapit siivotaan 3.-5.10. välisenä aikana. Voitteko merkitä S:\KLIIN\CRC\Laminaarit Laminars ja S:\KLIIN\CRC\Vetokaapit Fume hoods kansioihin päivämäärät jolloin vetokaapit ja laminaarit voi siivota. Pyrkikää jakamaan laminaarit/vetokaapit tasaisesti kolmelle päivälle. Laminaarit ja vetokaapit pitää tyhjentää siivousta edeltävän päivänä. Terv. Antti

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Opetusnäytetilaisuus 30. syyskuuta / Test lecture event on September 30
by Anne Vainionpää 12 Dec '24

12 Dec '24

Hyvä tiedekunnan väki, Syyskauden ensimmäinen opetusnäytetilaisuus järjestetään tulevana maanantaina, 30. syyskuuta klo 12.00 alkaen. Tilaisuutta pääsee seuraamaan Patologian salissa P117. Dosentin arvoa hakevan henkilön on osoitettava hyvä opetustaito, joten opetusnäyte on tärkeä osa dosentuurihakuprosessia. Meillä on tilaisuus päästä seuraamaan seuraavia 15 minuutin esityksiä: LT Anu-Helmi Halt: ADHD:n tunnistaminen aikuisilla LT Sanna Iivanainen: Immuuniaktivaation vapauttajien haittavaikutukset ja niiden hallinta syövän hoidossa TkT Ville-Petteri Mäkinen: Keskeiset sydän- ja verisuonitautien riskitekijät kehdosta hautaan Tilaisuutta voi seurata myös etäyhteydellä. Tässä on siihen linkki: https://oulu.zoom.us/j/63403198788?pwd=dVhZTjU1cXdsMnlRRS9vZUZlcTd4dz09 Luvassa on mielenkiintoisia esityksiä, tervetuloa tilaisuuteen mukaan! ****************** Dear English speaking people, On next Monday, September 30 we shall have the first test lecture event for the autumn season. The event will be arranged at the Pathology lecture hall P117, at 12.00. The speakers and the lecture titles will be found above. If you are not able to join the event at the lecture hall, you can follow the presentations remotely; the link is also above. Welcome to listen to interesting 15 minutes presentations! Best wishes, Anne **************** Anne Vainionpää Management assistant Faculty of Medicine

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DWA-välinehuolto: autoclaving of biological waste is only done in Kieppi, still!
by Virpi Glumoff 10 Dec '24

10 Dec '24

Dear All Just a kind reminder that the waste autoclave at FBMM site is broken. Please do not bring any biological waste to FBMM autoclave rooms, but instead carry the waste to Kieppi facility. I will inform you as soon as the autoclave is repaired. -virpi ________________________________ Lähetetty: perjantai 13. syyskuuta 2024 11.25 Vastaanottaja: fbmm <fbmm(a)lists.oulu.fi<mailto:fbmm@lists.oulu.fi>>; Kieppi 2nd Floor Labs <KieppiSecondFloorLabs(a)unioulu.oulu.fi<mailto:KieppiSecondFloorLabs@unioulu.oulu.fi>>; crc(a)lists.oulu.fi<mailto:crc@lists.oulu.fi> <crc(a)lists.oulu.fi<mailto:crc@lists.oulu.fi>>; bco-kieppi(a)lists.oulu.fi<mailto:bco-kieppi@lists.oulu.fi> <bco-kieppi(a)lists.oulu.fi<mailto:bco-kieppi@lists.oulu.fi>>; bco(a)lists.oulu.fi<mailto:bco@lists.oulu.fi> (bco(a)lists.oulu.fi<mailto:bco@lists.oulu.fi>) <bco(a)lists.oulu.fi<mailto:bco@lists.oulu.fi>>; can_trans(a)lists.oulu.fi<mailto:can_trans@lists.oulu.fi> <can_trans(a)lists.oulu.fi<mailto:can_trans@lists.oulu.fi>>; anakoomikot(a)lists.oulu.fi<mailto:anakoomikot@lists.oulu.fi> <anakoomikot(a)lists.oulu.fi<mailto:anakoomikot@lists.oulu.fi>>; biolaaket(a)lists.oulu.fi<mailto:biolaaket@lists.oulu.fi> <biolaaket(a)lists.oulu.fi<mailto:biolaaket@lists.oulu.fi>> Kopio: Pirkko Viitala <pirkko.viitala(a)oulu.fi<mailto:pirkko.viitala@oulu.fi>>; Virpi Glumoff <virpi.glumoff(a)oulu.fi<mailto:virpi.glumoff@oulu.fi>>; DWA-valinehuolto-staff <DWA-valinehuolto(a)oulu.fi<mailto:DWA-valinehuolto@oulu.fi>>; Katja Porvari <katja.porvari(a)oulu.fi<mailto:katja.porvari@oulu.fi>> Aihe: [Crc] DWA-välinehuolto: autoclaving of biological waste moves to Kieppi because of the broken waste autoclave Dear all Unfortunately, from today, September 13th, we have to start autoclaving all biological waste in Kieppi. Please, carry all your biological waste for disposal in Kieppi DWA unit room 237B. You will find clean autoclave bins in room 239B. The waste autoclave in FBMM site cannot be used because of a broken pump. I will inform you when the waste autoclave is back in use and waste will be autoclaved in FBMM site again. The dish washing and clean item autoclaving remains in FBMM DWA unit. There is NO washing service in Kieppi. BR virpi ............................................................................. Virpi Glumoff FT, dos., laboratoriopäällikkö Lääketieteellinen tiedekunta, Oulun yliopisto PL 5000 (Aapistie 5A) 90014 Oulun yliopisto PhD, Adjunct Professor, Laboratory Manager Faculty of Medicine, University of Oulu PO BOX 5000 (Aapistie 5A) FI-90014 UNIVERSITY OF OULU virpi.glumoff(a)oulu.fi<mailto:virpi.glumoff@oulu.fi> tel: +358 294 485890 .............................................................................

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Finnish 3Rs Annual Symposium and Workshops in Oulu, 4-6 November
by Reetta Hinttala 30 Oct '24

30 Oct '24

Dear All, We invite everyone (researchers, technicians, caretakers) involved in biomedical research with animal models and cell culture-based novel approaches to hear top level presentations by international and national experts on implementing 3R principles in practice. We have prepared two workshops and more than 10 talks by top experts in the field for the three-day event. This is also a good opportunity to present your own research either by poster or short oral talk. Abstract submission is open here<https://link.webropolsurveys.com/Participation/Public/24bcc537-1eec-483f-a1…>. We accept abstracts for oral presentations from doctoral researchers, post docs and PIs until 30 September and for posters until 1 November. Abstracts selected for oral presentations will be announced on 11 October. For more information about the topics and sessions, have a look at the program below! Finnish 3Rs Annual Symposium University of Oulu, 4-6 November 2024 Kontinkangas campus, Aapistie 5A WORKSHOPS Early Career Researchers - use the opportunity to brush up your skill and knowledge in power analysis and experimental design in two dedicated workshops (WS). Note: Places for the workshops are limited. Each workshop can accommodate 16-20 participants. Reserve your space in advance! Monday, 4 November 2024 (room 487B) 13.00-16.00 Power analysis - Petteri Piepponen (University of Helsinki, Finland) We will have some hands-on power analysis exercises in the workshop, so please bring your laptop along, and install the G*Power software beforehand. G*Power is a tool to compute statistical power analyses for many different t tests, and it is available from the University of Dusseldorf for free for both Mac and Windows. You can download the program from here<https://www.psychologie.hhu.de/arbeitsgruppen/allgemeine-psychologie-und-ar…>. Registration for the Power Analysis Workshop is open until 18 October 2024. To register, click here<https://link.webropolsurveys.com/Participation/Public/a32f0fcc-adda-4a24-a4…>. Tuesday, 5 November 2024 (room 487B) 9.00-12.00 What’s in a hypothesis? What are exploratory and confirmatory studies, and why is it important to be able to tell the difference? - Otto Kalliokoski (University of Copenhagen, Denmark) In this workshop, we will together look at why formulating a clear hypothesis matters. What happens if we get things wrong? We will use some real-life examples to look at the fundamental differences between exploratory and confirmatory studies. What is the nature of the study you are planning currently? Through some light group discussion, I hope to highlight that the devil really is in the details. You may even look at published studies somewhat differently afterwards. During this three-hour session, we will talk about how we formulate a hypothesis (which is a lot harder than many researchers think!). We will also briefly talk about future trends. How can we do things better? How do we go about pre-registering a study? What are registered reports? The workshop has no pre-requisites, but it will primarily benefit those who work with – or aim to work with – creating their own studies. PhD students or professors – everyone can benefit from giving their hypotheses some extra thought. Kindly bring a laptop or tablet to the workshop (a phone will do in a pinch) as there will be interactive elements to the session. The workshop will be in English, but questions can also be asked in Finnish. Registration for the Experimental Design Workshop is open until 18 October 2024. To register, click here<https://link.webropolsurveys.com/Participation/Public/112d3c65-144f-4c42-89…>. SYMPOSIUM Tuesday, 5 November 2024 (101A, Leena Palotie Hall) Session 1 Chair: Mikko Airavaara (University of Helsinki, Finland) 13:15-13:30 Welcoming words from the organizers 13:30-14:00 Integrated approaches in toxicology and pharmacology - Dario Greco (University of Tampere, Finland) 14:00-14:30 Anesthetic influence on cerebrospinal fluid dynamics in rodents - Daniel Persson (University of Helsinki, Finland) 14:30-15:15 Coffee and Posters 15:15-15:30 Short oral presentations from abstracts 15:30-16:00 Breeding of laboratory animals - complexities around simple biology - Thorsten Buch (University of Zurich, Switzerland) Wednesday, 6 November 2024 (101A, Leena Palotie Hall) Session 2 Chair: Johanna Englund (University of Helsinki, Finland) 9:00-9:35 Refining models of cardiac fibrosis, from mice to dish - Andreas Romaine (University of Oslo, Norway) 9:35-10:05 Modelling liver complexity with organoids - Anna Dowbaj (Max Planck Institute of Cell Biology and Genetics, Germany) 10:05-10:35 Coffee Break Session 3 Chair: Vootele Voikar (University of Helsinki, Finland) 10:35-11:10 The 3Hs initiative: Housing, Handling and Habituation methods for rodents - Megan Jackson (University of Bristol, UK) 11:10-11:40 Mastering Mouse Habituation and its Effects on Biomedical Research Outcomes - Julia Swan (University of Eastern Finland, Finland) 11:40- 12:00 Short oral presentations from abstracts 12:00-13:30 Lunch and Posters Session 4 Chair: Hanna-Marja Voipio (University of Oulu, Finland) 13:30-14:05 The LAG-R guidelines, a framework for standardizing and improving laboratory animal genetic reporting - Guillaume Pavlovic (Institut Clinique de la Souris, France) 14:05-14:35 Refinement of preclinical research - a focus on experimental design - Gillian Currie (University of Edinburgh, UK) 14:35-15:20 KEYNOTE: How common are fraudulent animal studies and how do they impact us? - Otto Kalliokoski (University of Copenhagen, Denmark) 15:20-15.30 Discussion and closing words Attending the symposium supports your continuing professional development (CPD). Doctoral researchers can earn additional study credits by presenting their work at the symposium (short oral communication and/or poster). Registration for the Symposium is open until 1 November 2024. To register, click here<https://link.webropolsurveys.com/Participation/Public/24bcc537-1eec-483f-a1…>. For additional information and questions, please contact Reetta Hinttala at reetta.hinttala(a)oulu.fi<mailto:reetta.hinttala@oulu.fi>. Organized by: 3R Centre Finland, Fin3R; Animal Welfare Body of Oulu Laboratory Animal Centre; Biocenter Oulu; Health and Biosciences Doctoral Programme, University of Oulu Graduate School Organizing committee: Reetta Hinttala, Mikko Airavaara, Johanna Englund, Anne Heikkinen, Satu Kuure, Sakari Laaksonen, Vootele Voikar and Hanna-Marja Voipio.

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Kontinkangas Research Seminar, Sept 26 at 15.15-16 in F202
by Pirkko Huhtala 10 Oct '24

10 Oct '24

Dear all, On Thursday September 26 we will have a Kontinkangas Research Seminar at 15.15-16 in F202. The speaker is Professor Reetta Hinttala, Research Unit of Clinical Medicine, Faculty of Medicine, Coordinator of Transgenic and Tissue Phenotyping Core Facility, Biocenter Oulu, University of Oulu. The title of her presentation is "Early-onset neurological multiorgan diseases and their research models". Her research interests include Neurological and multiorgan diseases in children, Rare genetic diseases, and In vitro and in vivo disease models. More information can be found here: https://www.oulu.fi/en/research-groups/pediatric-neurology-group Welcome everybody! No registration required. Coffee is served during networking session 20 min before the presentation time. Field specific credits can be earned according to UniOGS recommendations<https://www.oulu.fi/en/research/graduate-school/thesis-requirements-and-stu…> (attendance at scientific seminars for 10 hours: 0,5ECTS) If you would like to have separate discussions with the speaker, please contact Teija.luoto(a)oulu.fi<mailto:Teija.luoto@oulu.fi> who will set up the meeting time. Organized by Biocenter Oulu and Health and Biosciences Doctoral Programme Kind regards Pirkko Huhtala Time and venue Speaker Title September 12 15.15-16 P117 Wojciech Chrzanowski Nano-Bio-Characterization Facility, Faculty of Medicine and Health, University of Sydney, Australia Made by Cells for Cells: Harnessing Extracellular Vesicles for a Healthier and More Sustainable Future September 26 15.15-16 F202 Reetta Hinttala Research Unit of Clinical Medicine, Faculty of Medicine, University of Oulu Early-onset neurological multiorgan diseases and their research models October 3 8.30-16 101A Leena Palotie Hall Biocenter Oulu Day Revolutionising health with omics Separate Programme October 4 Ad-Hoc seminar 10.00-11 F202 Katsuyuki Yugi Team Leader from the Laboratory for Integrated Cellular Systems, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan Trans-omics: integration of multiple omic data on the basis of reaction kinetics October 7 11.45-13, F202 Nobel Prize in Physiology or Medicine 2024 Separate Programme October 10 15.15-16 F202 Julián Aragonés López Faculty of Medicine, Autonomous University of Madrid, Spain Role of hypoxia inducible factors (HIFs)-dependent metabolism rewiring in tumor cell biology October 17 15.15-16 F202 Dagmar Wachten Department of Biophysical Imaging, Institute of Innate Immunity, University of Bonn, Germany Shedding light on ciliary signaling in health and disease October 31 15.15-16 F101 Liisa Kauppi Systems Oncology Research Program, University of Helsinki Measuring and exploiting defective DNA repair in epithelial cancers November 21 15.15-16 F202 Jeroen Rouwkema Department of Biomechanical Engineering, University of Twente, The Netherlands Chemical and mechanical perturbation of in vitro vascular network organization November 28 13.15-14 P117 AND 15.15-16 F202 Outi Kilpivaara Department of Medical and Clinical Genetics, University of Helsinki Alexander Nyström Department of Dermatology, Medical Center, University of Freiburg, Germany TBA Understanding the ECM through genetic diseases - prospects for wound healing and fibrosis therapies December 12 14.15-16 101A Leena Palotie Hall Valeria Orlova Department of Anatomy and Embryology, Leiden University Medical Center, The Netherlands Simo Franssila Dept. of Chemistry and Materials Science and Micronova Nanofabrication Center Aalto University, Helsinki Next-Generation Vascular Disease Models Using Patient-Derived Human Induced Pluripotent Stem Cells (hiPSCs) TBA December 17 12.30-15.30 101A Leena Palotie Hall BCO Discovery of the Year Separate programme TBA Pirkko Huhtala, PhD Coordinator Biocenter Oulu, University of Oulu e-mail: pirkko.huhtala(a)oulu.fi<mailto:pirkko.huhtala@oulu.fi> tel: +358-294 486101, + 358-40 1897467 Street address: Room 476B, Aapistie 5A, FIN-90220 Oulu Mailing address: PO Box 5000, FIN-90014 University of Oulu, Finland www.oulu.fi/biocenter<http://www.oulu.fi/biocenter>

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Mykoplasmatestin tulokset
by Anja Heikkinen 30 Sep '24

30 Sep '24

Hei, kaikki mykoplasmatestin näytteet olivat puhtaita. Liitteistä löytyy näytejärjestys ja geelikuvat. Terveisin Anja

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Crc September 2024